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dc.contributor.authorPádua, Ana Patricia Sousa Lopes dept_BR
dc.contributor.authorKoehler, Alessandrapt_BR
dc.contributor.authorPagani, Danielle Machadopt_BR
dc.contributor.authorBezerra, Jadson Diogo Pereirapt_BR
dc.contributor.authorMotta, Cristina Maria de Souzapt_BR
dc.contributor.authorScroferneker, Maria Luciapt_BR
dc.date.accessioned2023-03-29T03:25:26Zpt_BR
dc.date.issued2022pt_BR
dc.identifier.issn1517-8382pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/256419pt_BR
dc.description.abstractThe present study reports a new occurrence of Rhinocladiella similis isolated as an endophytic fungus in the Caatinga dry tropical forest in Brazil and describes its antifungal susceptibility. The isolate R. similis URM 7800 was obtained from leaves of the medicinal plant Myracrodruon urundeuva. Its morphological characterization was performed on potato dextrose agar medium and molecular analysis using the ITS rDNA sequence. The antifungal susceptibility profile was defined using the Clinical and Laboratory Standards Institute (CLSI) protocol M38-A2. The colony of isolate URM 7800 showed slow growth, with an olivaceous-gray color and powdery mycelium; in microculture, it showed the typical features of R. similis. In the antifungal susceptibility test, isolate URM 7800 showed high minimal inhibitory concentration (MIC) values for amphotericin B (>16 μg/mL), voriconazole (16 μg/mL), terbinafine (>0.5 μg/mL), and caspofungin (>8 μg/mL), among other antifungal drugs. Pathogenic melanized fungi are frequently isolated in environments where humans may be exposed, and these data show that it is essential to know if these isolates possess antifungal resistance.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofBrazilian journal of microbiology. São Paulo, SP. Vol. 53, no. 4 (Dec. 2022), p. 2093-2100pt_BR
dc.rightsOpen Accessen
dc.subjectAntifúngicospt_BR
dc.subjectAntifungal susceptibilityen
dc.subjectDHN-melaninen
dc.subjectEndófitospt_BR
dc.subjectRhinocladiellapt_BR
dc.subjectDry tropical foresten
dc.subjectEndophytesen
dc.subjectHerpotrichiellaceaeen
dc.titleAntifungal susceptibility of the endophytic fungus Rhinocladiella similis (URM 7800) isolated from the Caatinga dry forest in Brazilpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001164028pt_BR
dc.type.originNacionalpt_BR


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