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dc.contributor.authorOrso, Catianept_BR
dc.contributor.authorCony, Bruna Souza de Limapt_BR
dc.contributor.authorSilva, J. P.pt_BR
dc.contributor.authorFurtado, Júlio César Veirapt_BR
dc.contributor.authorMann, Michele Bertonipt_BR
dc.contributor.authorFrazzon, Jeversonpt_BR
dc.contributor.authorFrazzon, Ana Paula Guedespt_BR
dc.contributor.authorAndretta, Inespt_BR
dc.contributor.authorRibeiro, Andrea Machado Lealpt_BR
dc.date.accessioned2023-03-29T03:25:18Zpt_BR
dc.date.issued2022pt_BR
dc.identifier.issn0032-5791pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/256411pt_BR
dc.description.abstractThis experiment determined if 2% of gelatin, to improve the levels of proline and glycine in the diet, and 70 mg/kg of vitamin E supplementation would relieve the impaired performance of male Cobb broilers vaccinated for coccidiosis. Half of the chicks were vaccinated via water (live oocysts), while the other half received medication (salinomycin) in the feed until 35 d of age. The effects of coccidiosis vaccine on performance and mRNA levels of genes involved in mucin synthesis, cytokines, trefoil family factor-2 (TFF2), and metabolic processes (CD36) in the jejunum of broilers were measured. Vaccination negatively affected performance in the first 21 d; however, the inclusion of gelatin and vitamin E reduced this negative response. Additionally, supplementation with these nutrients led to an improvement in broilers receiving the coccidiostat (P < 0.05). From 21 to 35 d, birds treated with gelatin and coccidiosis vaccine experienced better body weight gain than birds without gelatin and vitamin E (P < 0.05). Vaccinated chickens had decreased body weight and decreased anti-inflammatory cytokine expression. Fur- thermore, they had increased inflammatory cytokine expression, mucin 2 expression, and TFF2 compared to salinomycin-fed broilers (P < 0.05). Transcripts for IL- 1B, IFN-y, MUC2, TFF2 were decreased while mRNAs for IL-4 and IL-10 increased in salinomycin-fed broilers compared to vaccinated broilers (P < 0.05). In conclusion, broilers vaccinated against coccidiosis increase their pro-inflammatory immune status and mucin expression compared to broilers receiving salinomycin. These events may contribute to lower performance in vaccinated broiler chicks. Moreover, vitamin E and gelatin can minimize the vaccine’s negative immune effects and promote better performance.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofPoultry science. Cambridge, UK. Vol. 101, no. 12 (Dec. 2022), 102206, 10 p.pt_BR
dc.rightsOpen Accessen
dc.subjectCoccidiosept_BR
dc.subjectCoccidiosisen
dc.subjectFrangopt_BR
dc.subjectNonessentialen
dc.subjectAmino acidsen
dc.subjectVacinaçãopt_BR
dc.subjectVaccineen
dc.subjectVitaminen
dc.titleEffect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin Ept_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001164097pt_BR
dc.type.originEstrangeiropt_BR


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