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dc.contributor.authorGonçalves, E.pt_BR
dc.contributor.authorCastro, Jose Augusto Sisson dept_BR
dc.contributor.authorGross, Jorge Luizpt_BR
dc.date.accessioned2022-08-19T04:44:26Zpt_BR
dc.date.issued1986pt_BR
dc.identifier.issn0100-879Xpt_BR
dc.identifier.urihttp://hdl.handle.net/10183/247375pt_BR
dc.description.abstract1. The effect of the standard 15 mCi dose of 131 I on the thyroid function of 25 patients from an endemic goiter region with toxic multinodular goiter of different sizes was determined. 2. The patients were followed for 1 to 5 years and 7 months (mean: 2 years and 10 months). Eighteen patients were treated with the antithyroid drugs propylthiouracil or methimazole before 1 3 1 I and seven only received 131 I. 3. All but three patients achieved euthyroidism after a single dose of 131 1. Two patients in the antithyroid treatment group became hypothyroid 2 months and 2 years after the isotope therapy, respectively. Pretreatment with antithyroid drugs did not significantly modify the effectiveness of 131 I treatment. 4. This simplified dose regimen of 131 I was effective in the treatment of hyperthyroidism caused by multinodular goiter in an endemic region, and the efficacy was independent of the size of the goiter.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas. Ribeirão Preto, SP. Vol. 19, no. 6 (1986), p. 723-729pt_BR
dc.rightsOpen Accessen
dc.subjectToxic multinodular goiteren
dc.subjectBócio endêmicopt_BR
dc.subject131 I therapyen
dc.subjectTireotoxicosept_BR
dc.subjectThyrotoxicosisen
dc.titleStandard dose 131 I therapy for toxic multinodular goiter in an endemic goiter regionpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000705880pt_BR
dc.type.originNacionalpt_BR


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