Show simple item record

dc.contributor.authorSantos, Leonardo Peterson dospt_BR
dc.contributor.authorEspírito Santo, Rafaela Cavalheiro dopt_BR
dc.contributor.authorPena, Émersonpt_BR
dc.contributor.authorDória, Lucas Denardipt_BR
dc.contributor.authorHax, Vanessapt_BR
dc.contributor.authorBrenol, Claiton Viegaspt_BR
dc.contributor.authorMonticielo, Odirlei Andrépt_BR
dc.contributor.authorChakr, Rafael Mendonça da Silvapt_BR
dc.contributor.authorXavier, Ricardo Machadopt_BR
dc.date.accessioned2022-07-28T04:45:42Zpt_BR
dc.date.issued2021pt_BR
dc.identifier.issn2075-4418pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/245621pt_BR
dc.description.abstractBackground: Rheumatoid arthritis (RA) is an autoimmune, inflammatory and chronic disease that may lead to loss of muscle mass, muscle strength and decreased functionality. Our objectives are to assess the quadriceps muscle morphology by ultrasound (MU) and verify its associations with clinical features, muscle strength and physical function in RA patients. Methods: In this cross-sectional study, RA women ( 18 years) were included. Morphological parameters in quadriceps muscle consisted of the muscle thickness and pennation angle of rectus femoris (RF), vastus intermedius (VI) and vastus lateralis (VL). RA activity was measured by a 28-joint disease activity score (DAS28), muscle strength by handgrip and chair stand tests, and physical function by health assessment questionnaire (HAQ), timed-up-and-go (TUG) test and short physical performance battery (SPPB). Results: Fifty-five patients were included (age: 56.73 9.46 years; DAS28: 3.08 1.29). Muscle thickness in RF, VI and VL were negatively associated with age (RF, p < 0.001; VI, p = 0.013; VL, p = 0.002) and disease duration (RF, p < 0.001; VI, p = 0.005; VL, p = 0.001), and were positively associated with handgrip strength (RF, p = 0.015; VI, p = 0.022; VL, p = 0.013). In addition, decreased muscle thickness in VI (p = 0.035) and a smaller pennation angle in RF (p = 0.030) were associated with higher DAS-28 scores. Conclusion: Quadriceps muscle morphology by ultrasound appears to be affected by age, disease duration, disease activity and muscle strength in patients with RA. MU can be a useful method to evaluate the impact of the disease on skeletal muscle.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofDiagnostics. Basel. Vol. 11 (2021), 2014, 15 p.pt_BR
dc.rightsOpen Accessen
dc.subjectRheumatoid arthritisen
dc.subjectArtrite reumatóidept_BR
dc.subjectMuscle massen
dc.subjectMúsculospt_BR
dc.subjectUltrasounden
dc.subjectSarcopeniapt_BR
dc.subjectMuscle strengthen
dc.subjectAntropometriapt_BR
dc.subjectForça muscularpt_BR
dc.subjectFunctionalityen
dc.subjectMulherespt_BR
dc.subjectSarcopeniaen
dc.titleMorphological parameters in quadriceps muscle were associated with clinical features and muscle strength of women with rheumatoid arthritis : a cross-sectional studypt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001146368pt_BR
dc.type.originEstrangeiropt_BR


Files in this item

Thumbnail
   

This item is licensed under a Creative Commons License

Show simple item record