Waterborne aripiprazole blunts the stress response in zebrafish
dc.contributor.author | Barcellos, Heloisa Helena de Alcantara | pt_BR |
dc.contributor.author | Kalichak, Fabiana | pt_BR |
dc.contributor.author | Rosa, João Gabriel Santos | pt_BR |
dc.contributor.author | Oliveira, Thiago Acosta | pt_BR |
dc.contributor.author | Koakoski, Gessi | pt_BR |
dc.contributor.author | Idalencio, Renan | pt_BR |
dc.contributor.author | Abreu, Murilo Sander de | pt_BR |
dc.contributor.author | Giacomini, Ana Cristina Vendrametto Varrone | pt_BR |
dc.contributor.author | Fagundes, Michele | pt_BR |
dc.contributor.author | Variani, Cristiane | pt_BR |
dc.contributor.author | Rossini, Mainara | pt_BR |
dc.contributor.author | Piato, Angelo Luis Stapassoli | pt_BR |
dc.contributor.author | Barcellos, Leonardo Jose Gil | pt_BR |
dc.date.accessioned | 2021-08-11T04:47:11Z | pt_BR |
dc.date.issued | 2016 | pt_BR |
dc.identifier.issn | 2045-2322 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/225520 | pt_BR |
dc.description.abstract | Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the environment. Although the mechanism of APPZ in the neuroendocrine axis is not yet determined, our results highlight that the presence of APPZ residues in the environment may interfere with the stress responses in fish. Since an adequate stress response is crucial to restore fish homeostasis after stressors, fish with impaired stress response may have trouble to cope with natural and/or imposed stressors with consequences to their welfare and survival. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Scientific reports. London. Vol. 6, article 37612, [4] p. | pt_BR |
dc.rights | Open Access | en |
dc.subject | Aripiprazol | pt_BR |
dc.subject | Environmental impact | en |
dc.subject | Águas residuais | pt_BR |
dc.subject | Stress and resilience | en |
dc.subject | Peixe-zebra | pt_BR |
dc.title | Waterborne aripiprazole blunts the stress response in zebrafish | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001022407 | pt_BR |
dc.type.origin | Estrangeiro | pt_BR |
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