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dc.contributor.authorPeruch, Thaispt_BR
dc.contributor.authorFeiten, Taiane dos Santospt_BR
dc.contributor.authorFlores, Josani Silvapt_BR
dc.contributor.authorDalcin, Paulo de Tarso Rothpt_BR
dc.contributor.authorZiegler, Brunapt_BR
dc.date.accessioned2021-04-28T04:30:03Zpt_BR
dc.date.issued2020pt_BR
dc.identifier.issn2357-9730pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/220284pt_BR
dc.description.abstractIntroduction: Inhalation therapy is a crucial part of the cystic fibrosis (CF) treatment regimen. Drugs that assist in mucociliary clearance and inhaled antibiotics are used by most patients. Methods: This is a cross-sectional study where patients with CF and their caregivers answered questionnaires regarding their adherence to inhalation therapy and QoL. Demographic, spirometric, and bacteriological data, as well as S-K scores and hospitalization frequencies were also collected. Results: We included 66 patients in this study; participants had a mean age of 12.3 years and Z-scores of -1.4 for forced expiratory volume in 1 second and 48.6 for body mass index. Patients were divided into 2 groups according to their self-reported adherence to inhalation therapy: high adherence (n = 46) and moderate/low adherence (n = 20). When comparing both groups, there was no statistically significant differences in age, sex, family income, and S-K score (p > 0.05). The high-adherence group had had shorter hospitalization periods in the previous year (p = 0.016) and presented better scores in the following domains of the QoL questionnaire: emotion (p = 0.006), eating (p = 0.041), treatment burden (p = 0.001), health perception (p = 0.001), and social (p = 0.046). Conclusions: A low self-reported adherence to inhalation therapy recommendations was associated with longer hospitalizations in the previous year and with a decrease in QoL in pediatric patients with CF.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofClinical and biomedical research. vol. 40, no. 2 (2020), p. 105-110.pt_BR
dc.rightsOpen Accessen
dc.subjectCystic fibrosisen
dc.subjectFibrose císticapt_BR
dc.subjectCriançapt_BR
dc.subjectAdherenceen
dc.subjectQualidade de vidapt_BR
dc.subjectNebulizationen
dc.subjectQuality of lifeen
dc.subjectCooperação e adesão ao tratamentopt_BR
dc.subjectTerapia respiratóriapt_BR
dc.subjectOxigenoterapiapt_BR
dc.titleAdherence to inhalation therapy and quality of life in children with cystic fibrosis : a cross-sectional studypt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001123673pt_BR
dc.type.originNacionalpt_BR


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