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dc.contributor.authorZanatta, Marilene de Souzapt_BR
dc.contributor.authorQuillfeldt, Jorge Albertopt_BR
dc.contributor.authorSchaeffer, Evelin Lisetept_BR
dc.contributor.authorSchmitz, Paulo Kroeffpt_BR
dc.contributor.authorQuevedo, João Luciano dept_BR
dc.contributor.authorMedina, Jorge Horáciopt_BR
dc.contributor.authorIzquierdo, Ivan Antoniopt_BR
dc.date.accessioned2010-04-24T04:15:41Zpt_BR
dc.date.issued1997pt_BR
dc.identifier.issn0100-879Xpt_BR
dc.identifier.urihttp://hdl.handle.net/10183/21199pt_BR
dc.description.abstractA total of 182 young adult male Wistar rats were bilaterally implanted with cannulae into the CA1 region of the dorsal hippocampus and into the amygdaloid nucleus, the entorhinal cortex, and the posterior parietal cortex. After recovery, the animals were trained in a stepdown inhibitory avoidance task. At various times after training (0, 30, 60 or 90 min) the animals received a 0.5-μl microinfusion of vehicle (saline) or 0.5 μg of muscimol dissolved in the vehicle. A retention test was carried out 24 h after training. Retention test performance was hindered by muscimol administered into both the hippocampus and amygdala at 0 but not at 30 min posttraining. The drug was amnestic when given into the entorhinal cortex 30, 60 or 90 min after training, or into the parietal cortex 60 or 90 min after training, but not before. These findings suggest a sequential entry in operation, during the posttraining period, of the hippocampus and amygdala, the entorhinal cortex, and the posterior parietal cortex in memory processing.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofRevista brasileira de pesquisas médicas e biológicas = Brazilian journal of medical and biological research. Ribeirão Preto, SP. Vol. 30, n. 2 (1997), p. 235-240pt_BR
dc.rightsOpen Accessen
dc.subjectTonsila do cerebelopt_BR
dc.subjectMemory consolidationen
dc.subjectMemóriapt_BR
dc.subjectHippocampus and amygdalaen
dc.subjectEntorhinal cortexen
dc.subjectHipocampopt_BR
dc.subjectCórtex cerebralpt_BR
dc.subjectParietal cortexen
dc.titleInvolvement of the hippocampus, amygdala, entorhinal cortex in memory consolidationpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000553945pt_BR
dc.type.originNacionalpt_BR


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