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Antibacterial activity of plant extracts from caatinga
dc.contributor.advisor | Macedo, Alexandre José | pt_BR |
dc.contributor.author | Amaral, Matheus Weiler do | pt_BR |
dc.date.accessioned | 2019-09-26T03:45:00Z | pt_BR |
dc.date.issued | 2011 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/199771 | pt_BR |
dc.description.abstract | The Brazilian semi-arid or Caatinga is a biome located almost exclusively in the Northeast region. The local communities demonstrated numerous uses for the plants, although few studies about the pharmacological properties of these species there have been developed. The present study evaluated the anti-Pseudomonas aeruginosa activity of aqueous extracts from Anadenanthera colubrina (Fabaceae, Mimosoideae), Myracrodruon urundeuva (Anacardiaceae), Commiphora leptophloeos (Burseraceae) and Pityrocarpa moniliformis (Fabaceae, Mimosoideae) and characterized some aspects of their mechanism of action. The minimal inhibitory concentration and the effect of the extracts on bacterial growth were determined by counting the colony forming units, as well as by antibacterial activity kinectics. Transmission electron microscopy was used to support the previous results. Phytochemical analysis was performed by TLC, bioautography and HPLC. All extracts showed a bacteriostatic effect under the experimental condition. Polyphenols, flavonoids, anthraquinones, anthrones, coumarins, peptides, terpens, steroids and saponins are the supposed class of compounds involved in the antibacterial activity. The four extracts are possible new sources of antibacterial agents against P. aeruginosa. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.rights | Open Access | en |
dc.subject | Anadenanthera colubrina | pt_BR |
dc.subject | Anadenanthera colubrina (Fabaceae Mimosoideae) | en |
dc.subject | Myracrodruon urundeuva | pt_BR |
dc.subject | Myracrodruon urundeuva (Anacardiaceae) | en |
dc.subject | Commiphora leptophloeos | pt_BR |
dc.subject | Commiphora leptophloeos (Burseraceae) | en |
dc.subject | Pityrocarpa moniliformis | pt_BR |
dc.subject | Pityrocarpa moniliformis (Fabaceae Mimosoideae) | en |
dc.subject | Pseudomonas aeruginosa | en |
dc.subject | Atividade antibacteriana | pt_BR |
dc.subject | Pseudomonas aeruginosa | pt_BR |
dc.subject | Antibacterial activity | en |
dc.subject | Caatinga, Região | pt_BR |
dc.title | Antibacterial activity of plant extracts from caatinga | pt_BR |
dc.type | Trabalho de conclusão de graduação | pt_BR |
dc.contributor.advisor-co | Giordani, Raquel Brandt | pt_BR |
dc.identifier.nrb | 000823519 | pt_BR |
dc.degree.grantor | Universidade Federal do Rio Grande do Sul | pt_BR |
dc.degree.department | Faculdade de Farmácia | pt_BR |
dc.degree.local | Porto Alegre, BR-RS | pt_BR |
dc.degree.date | 2011 | pt_BR |
dc.degree.graduation | Farmácia | pt_BR |
dc.degree.level | graduação | pt_BR |
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