Development of caprine preantral follicles after orthotopic autotransplantation of ovarian tissue
dc.contributor.author | Donfack, Nathalie Jiatsa | pt_BR |
dc.contributor.author | Alves, Kele Amaral | pt_BR |
dc.contributor.author | Alves, Bênner Geraldo | pt_BR |
dc.contributor.author | Martins, Leonardo Tondello | pt_BR |
dc.contributor.author | Mendez Calderon, Carlos Enrique | pt_BR |
dc.contributor.author | Gaudencio Neto, Saul | pt_BR |
dc.contributor.author | Aguiar, Luis Henrique de | pt_BR |
dc.contributor.author | Santos, Regiane Rodrigues dos | pt_BR |
dc.contributor.author | Domingues, Sheyla Farhayldes Souza | pt_BR |
dc.contributor.author | Bertolini, Marcelo | pt_BR |
dc.contributor.author | Figueiredo, José Ricardo de | pt_BR |
dc.contributor.author | Smitz, Johan | pt_BR |
dc.contributor.author | Rodrigues, Ana Paula Ribeiro | pt_BR |
dc.date.accessioned | 2019-05-29T02:43:22Z | pt_BR |
dc.date.issued | 2017 | pt_BR |
dc.identifier.issn | 2595-0711 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/194701 | pt_BR |
dc.description.abstract | Objective: The aim of this study was to evaluate the follicle morphology, density, development and hormone production after orthotopic autransplantation of fresh or vitrified goat ovarian tissue. Methods: Fresh and vitrified ovarian cortex was orthotopically autotransplanted for six months in two and three adults bilaterally ovariectomized goats, respectively. The animals were monitored during 196 days and blood samples collected. Results: It was observed that the percentage of morphologically normal preantral follicles (MNPF) after grafting of fresh ovarian tissue was similar to control. The follicular density in the fresh graft reduced significantly when compared to fresh control. unfortunately, after transplantation of vitrified tissue it was not possible to identified any follicles after recovery. Furthermore, the proportion of developing follicles was higher (P < 0.05) in the fresh auto-grafts than in control fragments. Moreover, progesterone plasma levels increased significantly from day 179 to day 195 of transplantation. Conclusion: In conclusion, orthotopic transplantation of fresh ovarian tissue was able to keep healthy the preantral follicles, as well as the restoration of goat endocrine function. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Human Reproduction Archives. São Paulo. Vol. 32, n. 3 (2017), e001217, 5 p. | pt_BR |
dc.rights | Open Access | en |
dc.subject | Caprinos | pt_BR |
dc.subject | Vitrification | en |
dc.subject | Folículo ovariano | pt_BR |
dc.subject | Endocrine function | en |
dc.subject | Preantral follicles | en |
dc.subject | Transplante autólogo | pt_BR |
dc.subject | Ovarian transplantation | en |
dc.title | Development of caprine preantral follicles after orthotopic autotransplantation of ovarian tissue | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001089032 | pt_BR |
dc.type.origin | Nacional | pt_BR |
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