Multidrug resistant organisms' incidence in a university Hospital in Porto Alegre

Abstract

Introduction: Multidrug-resistant organisms (MDRO) are a growing worldwide public health problem. Few therapeutic options remain available to treat infections caused by MDRO. Local actions should be implemented to reduce bacterial resistance and MDRO di usion. Objective: Evaluate the incidence of MDRO in the institution and assess the outcome of patients. Methods: Was performed a prospective cohort. Were included patients hospitalized between June 2010 and May 2011, with microbiological isolates, classi ed according to 2010 Hospital Infection Control Committee criteria. Patients were followed until their outcomes.Results: Were identi ed 981 multidrugresistant organisms in 808 patients. e median length of stay for the identi cation of the MDRO was 12 days (IQR 25-75%, 3-26 days). e monthly rate came to minimal and maximal amplitude of, respectively, 2.7 and 5.9 MDRO/1000 patient-days per period. During the studied period was not observed a signi cant increase in the incidence rate of MDRO at institution. Conclusion: Our ndings show that MDRO with major incidence was extended-spectrum -lactamase-producing organism and the vancomicin-resistant Enterococcus spp. e de nition of a local epidemiologic pro le of resistant organisms is important to drive preventive and therapeutic actions inside the institution.