Listar Ciencias Exactas y Naturales por autor "Glazier, James Alexander"
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Computer simulations of cell sorting due to differential adhesion
Zhang, Ying; Thomas, Gilberto Lima; Swat, Maciej; Shirinifard, Abbas; Glazier, James Alexander (2011) [Artículo de periódico]The actions of cell adhesion molecules, in particular, cadherins during embryonic development and morphogenesis more generally, regulate many aspects of cellular interactions, regulation and signaling. Often, a gradient ... -
Emergent stratification in solid tumors selects for reduced cohesion of tumor cells : a multi-cell, virtual-tissue model of tumor evolution using CompuCell3D
Swat, Maciej; Thomas, Gilberto Lima; Shirinifard, Abbas; Clendenon, Sherry G.; Glazier, James Alexander (2015) [Artículo de periódico]Tumor cells and structure both evolve due to heritable variation of cell behaviors and selection over periods of weeks to years (somatic evolution). Micro-environmental factors exert selection pressures on tumor-cell ... -
Grain growth from homogeneous initial conditions : anomalous grain growth and special scaling states
Jiang, Yi; Mombach, Jose Carlos Merino; Glazier, James Alexander (1995) [Artículo de periódico]We used the large-Q Potts model on a two-dimensional lattice to study the evolution of the disordered cluster developed from a perfect hexagonal lattice with a single defect. The distribution functions were not stable, ... -
Quantitative comparison between differential adhesion models and cell sorting in the presence and absence of fluctuations
Mombach, Jose Carlos Merino; Glazier, James Alexander; Raphael, Richard C.; Zajac, Mark (1995) [Artículo de periódico]We study the effect of inhibition of cell-membrane ruffling on cell sorting in experiments and simulations. We use aggregates of neural retinal and pigmented retinal cells obtained from chicken embryos and inhibit membrane ... -
Single cell motion aggregates of embryonic cells
Mombach, Jose Carlos Merino; Glazier, James Alexander (1996) [Artículo de periódico]We investigate the motion of individual pigmented retinal cells in aggregates of neural retinal cells obtained from chicken embryos. Individual cells in aggregates move randomly in the absence of chemical or adhesion ... -
Transcriptogram analysis reveals relationship between viral titer and gene sets responses during corona-virus infection
Almeida, Rita Maria Cunha de; Thomas, Gilberto Lima; Glazier, James Alexander (2022) [Artículo de periódico]To understand the difference between benign and severe outcomes after Coronavirus infection, we urgently need ways to clarify and quantify the time course of tissue and immune responses. Here we reanalyze 72-hour time-series ... -
Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
Almeida, Rita Maria Cunha de; Clendenon, Sherry G.; Richards, William Graham; Boedigheimer, Michael J.; Damore, Michael A.; Rossetti, Sandro; Harris, Peter C.; Herbert, Brittney Shea; Xu, Wei Min; Wandinger-Ness, Angela; Ward, Heather H.; Glazier, James Alexander; Bacallao, Robert L. (2016) [Artículo de periódico]Background: Autosomal dominant polycystic kidney disease (ADPKD) causes progressive loss of renal function in adults as a consequence of the accumulation of cysts. ADPKD is the most common genetic cause of end-stage renal ...