Browsing Health Sciences by Subject "Mesilato de imatinib"
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Betulinic acid-brosimine B hybrid compound has a synergistic effect with imatinib in chronic myeloid leukemia cell line, modulating apoptosis and autophagy
(2023) [Journal article]Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the formation of the BCR-ABL (breakpoint cluster region-Abelson) oncoprotein. As many patients display therapeutic resistance, the development ... -
What happens to intolerant, relapsed or refractory chronic myeloid leukemia patients without access to clinical trials?
(2019) [Journal article]Objective: To assess clinical outcomes of intolerant, relapsed or refractory patients who could not be treated with new tyrosine kinase inhibitors or experimental therapies. Methods: A retrospective cohort of 90 chronic ...