Now showing items 7583-7602 of 10565

    • Pesquisa, um dos pilares da história do HCPA 

      Macedo Neto, Amarilio Vieira de (2011) [Introductory and closing remarks]
    • Pessoas com doenças crônicas, as redes de atenção e a atenção primária à saúde 

      Chueiri, Patrícia Sampaio; Harzheim, Erno; Gauche, Heide; Vasconcelos, Lêda Lúcia Couto de (2014) [Journal article]
    • Pessoas idosas, covid-19 e saúde bucal : interlocuções, particularidades e reflexões 

      Baldisserotto, Julio; Santos, Camila Mello dos; De Marchi, Renato José; Martins, Aline Blaya; Bulgarelli, Alexandre Fávero (2020) [Journal article]
      Uma pandemia como a da COVID-19 faz a população mundial repensar várias questões envolvendo cuidado em saúde de pessoas idosas. Neste contexto, a assistência odontológica deve se adequar ao enfrentamento da referida pandemia. ...
    • Pessoas idosas institucionalizadas, transtornos depressivos e questões odontológicas : qual o estado da arte? 

      Lopes, Luiza Guilhermina de Oliveira; Santos, Camila Mello dos; Bulgarelli, Alexandre Fávero (2021) [Journal article]
      Objetivo: Fazer um mapeamento e uma discussão sobre o conhecimento científico envolvendo o objeto de pesquisa Condições de saúde bucal e depressão em idosos institucionalizados. Método: Revisão de Escopo do tipo mapeamento ...
    • Phacoemulsification and foldable acrylic IOL implantation in children with treated retinoblastoma 

      Tartarella, Marcia Beatriz; Britez-Colombi, Glória Fátima; Motono, Marcia; Chojniak, Martha Maria Motono; Fortes Filho, João Borges; Belfort Junior, Rubens (2012) [Journal article]
      Objetivos: Estudar os resultados da cirurgia da catarata induzida pela radioterapia para o tratamento do retinoblastoma em crianças. Métodos: Estudo retrospectivo intervencional em série de casos onde seis pacientes ...
    • Phaeohyphomycosis : a clinical-epidemiological and diagnostic study of eighteen cases in Rio Grande do Sul, Brazil 

      Severo, Cecília Bittencourt; Oliveira, Flávio de Mattos; Pilar, Emily Ferreira Salles; Severo, Luiz Carlos (2012) [Journal article]
      The goal of this study was to review 18 cases of phaeohyphomycosis in Rio Grande do Sul. The records of all of the patients with a diagnosis of phaeohyphomycosis between 1995-2010 were reviewed. Twelve of the 18 patients ...
    • Pharmacogenomics and cardiovascular disease : where are we and where do we go from here? 

      Stein, Ricardo; Beuren, Thaís Mariel Andara; Cela, Luis Ramudo; Lacerda, Filipe Ferrari Ribeiro de (2020) [Journal article]
      Pharmacogenomics (PGx) studies the interaction between genes and drugs. By analysis of specific regions of DNA, it is possible to obtain information on patient’s metabolization profile of a given drug, as well as the ...
    • Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers 

      Costa, Marisa Boff da; Picon, Paulo Dornelles; Sander, Guilherme Becker; Nodarse Cuni, Hugo; Valenzuela Silva, Carmen M; Páez Meireles, Rolando; Góes, Ana Carolina Magalhães Andrade; Batoreu, Nadia Maria; Maia, Maria de Lourdes de Sousa; Albuquerque, Elizabeth Maciel; Matos, Denise Cristina de Souza; López Saura, Pedro Antonio (2018) [Journal article]
      Background: Several countries have used pegylation technology to improve the pharmacokinetic properties of essential drugs. Recently, a novel interferon alfa-2b protein conjugated to four-branched 12 kDa polyethylene glycol ...
    • Pharmacological adherence to oral anticoagulant and factors that influence the International Normalized Ratio Stability 

      Ávila, Christiane Wahast; Aliti, Graziella Badin; Feijó, Maria Karolina Echer Ferreira; Silva, Eneida Rejane Rabelo da (2011) [Journal article]
      Este é um estudo transversal, desenvolvido com o objetivo de relacionar a estabilidade do índice de normatização internacional (INR), utilizado como parâmetro para monitorar os níveis de coagulação do sangue, com adesão, ...
    • Pharmacological properties of specioside from the stem bark of Tabebuia aurea 

      Nocchi, Samara Requena; Kato, Natália Naomi; Almeida, Júlio Menta de; Ferreira, Alda Maria Teixeira; Kadri, Mônica Cristina Toffoli; Meirelles, Lyvia Eloiza de Freitas; Damke, Gabrielle Marconi Zago Ferreira; Consolaro, Márcia Edilaine Lopes; Rigo, Graziela de Vargas; Macedo, Alexandre José; Tasca, Tiana; Reis, Sharon Vieira dos; Alves, Flávio Macedo; Carollo, Carlos Alexandre; Silva, Denise Brentan (2020) [Journal article]
      Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de Candolle. Tabebuia aurea (Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, ...
    • Pharmacological treatment and staging in bipolar disorder : evidence from clinical practice 

      Goi, Pedro Domingues; Bücker, Joana; Sulzbach, Miréia Fortes Vianna; Rosa, Adriane Ribeiro; Grande, Iria; Chendo, Inês; Sodré, Leonardo de Almeida; Kauer-Sant'Anna, Márcia; Silveira, Leonardo Evangelista da; Kunz, Maurício; Ceresér, Keila Maria Mendes; Gama, Clarissa Severino; Massuda, Raffael (2015) [Journal article]
      Objective: Staging models for medical diseases are widely used to guide treatment and prognosis. Bipolar disorder (BD) is a chronic condition and it is among the most disabling disorders in medicine. The staging model ...
    • Pharmacotherapy of bipolar disorder in children and adolescents : an update 

      Peruzzolo, Tatiana Lauxen; Tramontina, Silzá; Rohde, Luis Augusto Paim; Zeni, Cristian Patrick (2013) [Journal article]
      Objective: To review the options for acute and maintenance pharmacological treatment of bipolar disorder in children and adolescents, including the treatment of bipolar depression and comorbid attention deficit/hyperactivity ...
    • A phase 2, double-blind, placebo-controlled, randomized study of fresolimumab in patients with steroid-resistant primary focal segmental glomerulosclerosis 

      Vincenti, Flavio; Fervenza, Fernando Custodio; Campbell, Kirk Nicholas; Díaz, Montserrat M.; Gesualdo, Loreto; Nelson, Peter; Praga, Manuel; Radhakrishnan, Jai; Sellin, Lorenz K.; Singh, Ajay; Thornley-Brown, Denyse P.; Veronese, Francisco José Veríssimo; Accomando, Beverly; Engstrand, Sara; Ledbetter, Steven R.; Lin, Julie; Neylan, John F.; Tumlin, James A.; Focal Segmental Glomerulosclerosis Study Group (2017) [Journal article]
      Introduction: Steroid-resistant focal segmental glomerulosclerosis (SR-FSGS) is a common glomerulopathy associated with nephrotic range proteinuria. Treatment goals are reduction in proteinuria, which can delay end-stage ...
    • A phase II, randomized, double-blind, placebo controlled, dose-response trial of the melatonin effect on the pain threshold of healthy subjects 

      Stefani, Luciana Paula Cadore; Müller, Suzana; Torres, Iraci Lucena da Silva; Razzolini, Bruna Regis; Rozisky, Joanna Ripoll; Fregni, Felipe; Markus, Regina Pekelmann; Caumo, Wolnei (2013) [Journal article]
      Background: Previous studies have suggested that melatonin may produce antinociception through peripheral and central mechanisms. Based on the preliminary encouraging results of studies of the effects of melatonin on pain ...
    • pH effect on stability and kinetics degradation of nitazoxanide in solution 

      Barbosa, Fábio de Souza; Pezzi, Leonardo Capra; Sorrentino, Julia Medeiros; Steppe, Martin; Volpato, Nadia Maria; Mendez, Andreas Sebastian Loureiro (2020) [Journal article]
      Stability studies correspond to a set of tests designed to assess changes in the quality of a given drug over time and under the influence of a number of factors. Among these factors, pH plays an important role, due to the ...
    • Phenolic enriched extract of baccharis trimera presents anti-inflammatory and antioxidant activities 

      Oliveira, Cristiane Bernardes de; Comunello, Lucimara Nardi; Lunardelli, Adroaldo; Amaral, Robson Henrich; Pires, Melissa Guerra Simões; Silva, Gabriela Lucas da; Manfredini, Vanusa; Vargas, Carmen Regla; Gnoatto, Simone Cristina Baggio; Oliveira, Jarbas Rodrigues de; Gosmann, Grace (2012) [Journal article]
      Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities ...
    • Phenotype-oriented NGS panels for mucopolysaccharidoses : validation and potential use in the diagnostic flowchart 

      Fachin, Ana Carolina Brusius; Siebert, Marina; Leão, Delva Pereira; Málaga, Diana Elizabeth Rojas; Pasqualim, Gabriela; Trapp, Franciele Barbosa; Matte, Ursula da Silveira; Giugliani, Roberto; Leistner-Segal, Sandra (2019) [Journal article]
      Mucopolysaccharidosis (MPS) are a group of rare genetic disorders caused by deficiency in the activity of specific lysosomal enzymes required for the degradation of glycosaminoglycans (GAGs). A defect in the activity of ...
    • Phenotyping and genotyping methods applied to investigate the relatedness of brazilian isolates of enterobacter cloacae 

      Darini, A.L.C.; Magalhães, V.D.; Levy, C.L.; Barth, Afonso Luis; Coscina, A.L. (1999) [Journal article]
      In order to evaluate the resolving power of several typing methods to identify relatedness among Brazilian strains of Enterobacter cloacae, we selected twenty isolates from different patients on three wards of a University ...
    • Phenylketonuria and gut microbiota : a controlled study based on next-generation sequencing 

      Oliveira, Felipe Pinheiro de; Mendes, Roberta Hack; Dobbler, Priscila Caroline Thiago; Mai, Volker; Pylro, Victor Satler; Waugh, Sheldon G.; Vairo, Filippo Pinto e; Refosco, Lilia Farret; Roesch, Luiz Fernando Wurdig; Schwartz, Ida Vanessa Doederlein (2016) [Journal article]
      Phenylketonuria (PKU) is an inborn error of metabolism associated with high blood levels of phenylalanine (Phe). A Phe-restricted diet supplemented with L-amino acids is the main treatment strategy for this disease; if ...
    • PH e titrabilidade ácida de sucos artificiais de limão 

      Corso, Ana Carolina; Hugo, Fernando Neves; Padilha, Dalva Maria Pereira (2002) [Journal article]