• Waterborne aripiprazole blunts the stress response in zebrafish 

      Barcellos, Heloisa Helena de Alcantara; Kalichak, Fabiana; Rosa, João Gabriel Santos; Oliveira, Thiago Acosta; Koakoski, Gessi; Idalencio, Renan; Abreu, Murilo Sander de; Giacomini, Ana Cristina Vendrametto Varrone; Fagundes, Michele; Variani, Cristiane; Rossini, Mainara; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2016) [Artigo de periódico]
      Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the ...
    • Waterborne risperidone decreases stress response in zebrafish 

      Idalencio, Renan; Kalichak, Fabiana; Rosa, João Gabriel Santos; Oliveira, Tiago Acosta de; Koakoski, Gessi; Gusso, Darlan; Abreu, Murilo Sander de; Giacomini, Ana Cristina Vendrametto Varrone; Barcellos, Heloisa Helena de Alcantara; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2015) [Artigo de periódico]
      The presence of drugs and their metabolites in surface waters and municipal effluents has been reported in several studies, but its impacts on aquatic organisms are not yet well understood. This study investigated the ...
    • Were sea level changes during the pleistocene in the south atlantic coastal plain a driver of speciation in Petunia (Solanaceae)? 

      Fregonezi, Aline Mitcheli Carvalho Ramos; Fregonezi, Jeferson Nunes; Cybis, Gabriela Bettella; Fagundes, Nelson Jurandi Rosa; Bonatto, Sandro Luis; Freitas, Loreta Brandão de (2015) [Artigo de periódico]
      Background: Quaternary climatic changes led to variations in sea level and these variations played a significant role in the generation of marine terrace deposits in the South Atlantic Coastal Plain. The main consequence ...
    • What could be the fate of secondary contact zones between closely related plant species? 

      Schnitzler, Carolina Kaiser; Turchetto, Caroline; Teixeira, Marcelo Costa; Freitas, Loreta Brandão de (2020) [Artigo de periódico]
      Interspecific hybridization has been fundamental in plant evolution. Nevertheless, the fate of hybrid zones throughout the generations remains poorly addressed. We analyzed a pair of recently diverged, interfertile, and ...
    • What is new for an old molecule? : Systematic review and recommendations on the use of resveratrol 

      Vang, Ole; Ahmad, Nihal; Baile, Clifton A.; Baur, Joseph A.; Brown, Karen; Csiszar, Anna; Das, Dipak K.; Delmas, Dominique; Gottfried, Carmem Juracy Silveira; Lin, Hung-Yun; Ma, Qing-Yong; Mukhopadhyay, Partha; Nalini, Namasivayam; Pezzuto, John M.; Richard, Tristan; Shukla, Yogeshwer; Surh, Young-Joon; Szekeres, Thomas; Szkudelski, Tomasz; Walle, Thomas; Wu, Joseph M. (2011) [Artigo de periódico]
      Background: Resveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. ...
    • Where are the bats? An environmental complementarity analysis in a megadiverse country 

      Aguiar, Ludmilla Moura Souza; Pereira, Maria João Veloso da Costa Ramos; Zortéa, Marlon; Machado, Ricardo Bomfim (2020) [Artigo de periódico]
      Aim: Field surveys are necessary to overcome Wallacean shortfalls. The task is even more important when human pressure on tropical—megadiverse—ecosystems is con sidered. However, due to financial constraints, spatial and ...
    • Which fish is this? Fishers know more than 100 fish species in megadiverse tropical rivers 

      Silvano, Renato Azevedo Matias; Pereyra, Paula Evelyn Rubira; Begossi, Alpina; Hallwass, Gustavo (2022) [Artigo de periódico]
      Ethnobiological studies on folk, common, or popular names that fishers use to identify fish can help improve fisheries monitoring and collaborations between fishers and researchers. This study investigates fishers’ knowledge ...
    • Which is the best in silico program for the Missense Variations in IDUA gene? A comparison of 33 programs plus a conservation score and evaluation of 586 missense variants 

      Borges, Pâmella; Pasqualim, Gabriela; Matte, Ursula da Silveira (2021) [Artigo de periódico]
      Mucopolysaccharidosis type I (MPS I) is an autosomal recessive disease characterized by the deficiency of alpha-L-iduronidase (IDUA), an enzyme involved in glycosaminoglycan degradation. More than 200 disease-causing ...
    • White matter lesions in Fabry disease before and after enzyme replacement therapy : a 2-year follow-up 

      Jardim, Laura Bannach; Aesse, Flávio Franciosi; Vedolin, Leonardo Modesti; Pitta-Pinheiro, Cláudio de Faria; Marconato, João; Burin, Maira Graeff; Cecchin, Cláudia Rafaela; Netto, Cristina Brinckmann Oliveira; Matte, Ursula da Silveira; Pereira, Fernanda dos Santos; Kalakun, Luciane; Giugliani, Roberto (2006) [Artigo de periódico]
      Objetivo: Relatar os achados neurológicos e de imagem do sistema nervoso central (SNC), observados durante 24 meses de tratamento de reposição enzimática (ERT) com agalsidase-alfa, em pacientes com a doença de Fabry (FD). ...
    • Whole-genome sequencing-based characterization of Streptomyces sp. 6(4) : focus on natural product 

      Borba, Marcela Proença; Witusk, João Paulo Duarte; Cunha, Débora Marchesan; Morales, Daiana de Lima; Martins, Andreza Francisco; Van der Sand, Sueli Terezinha (2023) [Artigo de periódico]
      We have sequenced the whole genome of Streptomyces sp. 6(4) isolated from tomato roots that presents antifungal activity against phytopathogenic fungi, mainly Bipolaris sorokiniana. The genome has almost 7Mb and 3368 ...
    • Why is congenital Zika syndrome asymmetrically distributed among human populations? 

      Barbeito Andrés, Jimena; Faccini, Lavinia Schuler; Garcez, Patricia Pestana (2018) [Artigo de periódico]
      Zika virus (ZIKV) is a health burden due to the severe neurological abnormalities that arise after congenital infection. Although multiple experimental studies have linked ZIKV with neural birth defects, the scientific ...
    • Why we need to use and which mask types are effective against the novel coronavirus (COVID-19)? 

      Jotz, Geraldo Pereira; Bittencourt, Aline Gomes (2020) [Texto de apresentação/encerramento]
    • Wild boar diet and its implications on agriculture and biodiversity in Brazilian forest–grassland ecoregions 

      Cervo, Isabele Bisognin; Guadagnin, Demétrio Luís (2020) [Artigo de periódico]
      Wild boar diet and its implications on agriculture and biodiversity in Brazilian forest–grassland ecoregions. We aimed to describe the composition of Sus scrofa diet in three Brazilian ecoregions characterized by a mosaic ...
    • Wind farm bat fatalities in southern Brazil: temporal patterns and influence of environmental factors 

      Amaral, Izidoro Sarmento do; Pereira, Maria João Veloso da Costa Ramos; Mäder, Aurélea; Rosa, Marlon Ferraz da; Pereira, Jéssica Bandeira; Oliveira, Larissa Rosa de (2020) [Artigo de periódico]
      Energy demand created by the present model of economic growth has transformed the natural land scape. Changes in megadiverse environments should be accompanied by studies that describe and predict the effects of these ...
    • Women with primary ovarian insufficiency have lower bone mineral density 

      Amarante, Fernanda do; Vilodre, Luiz Cezar Fernandes; Maturana, Maria Augusta; Spritzer, Poli Mara (2011) [Artigo de periódico]
      The aim of the present study was to assess the prevalence of osteoporosis in a sample of 32 patients with spontaneous primary ovarian insufficiency (POI) in comparison to reference groups of 25 pre- and 55 postmenopausal ...
    • Worldwide genetic variation at the 3´-UTR region of the LDLR gene : possible influence of natural selection 

      Fagundes, Nelson Jurandi Rosa; Salzano, Francisco Mauro; Batzer, Mark A.; Deininger, Prescott L.; Bonatto, Sandro Luis (2005) [Artigo de periódico]
      The low density lipoprotein receptor gene (LDLR) contains many Alu insertions, and is especially Alu-rich at its 3 -untranslated region (3 -UTR). Previous studies suggested that the LDLR 3 -UTR could regulate gene expression ...
    • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016 : a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults 

      NCD Risk Factor Collaboration; Bentham, James; Zuñiga Cisneros, Julio; Ezzati, Majid; Fuchs, Flávio Danni; Fuchs, Sandra Cristina Pereira Costa; Moreira, Leila Beltrami (2017) [Artigo de periódico]
      Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) ...
    • Xenoestrogênios : o exemplo do bisfenol-a 

      Goloubkova, Tatiana; Spritzer, Poli Mara (2000) [Artigo de periódico]
      Evidências acumuladas indicam que a saúde dos seres humanos, animais e espécies selvagens pode sofrer conseqüências adversas da exposição a produtos químicos presentes no meio ambiente e que interagem com o sistema endócrino, ...
    • X-linked adrenoleukodystrophy : clinical and laboratory findings in 15 brazilian patients 

      Vargas, Carmen Regla; Coelho, Daniela de Moura; Barschak, Alethea Gatto; Souza, Carolina Fischinger Moura de; Puga, Ana Cristina Scheidt; Schwartz, Ida Vanessa Doederlein; Jardim, Laura Bannach; Giugliani, Roberto (2000) [Artigo de periódico]
      Adrenoleucodistrofia (X-ALD) é uma desordem peroxissomal com padrão de herança ligada ao X, fenotipicamente heterogênea, caracterizada por uma progressiva desmielinização da substância branca do sistema nervoso central e ...
    • Y-chromosome biallelic polymorphisms and native american population structure 

      Bortolini, Maria Cátira; Salzano, Francisco Mauro; Bau, Claiton Henrique Dotto; Layrisse, Zulay; Petzl-Erler, Maria Luiza; Tsuneto, Luiza T.; Hill, Kim R.; Hurtado, Ana Magdalena; Castro-de-Guerra, Dinorah C.; Bedoya, Gabriel; Ruiz-Linares, Andres (2002) [Artigo de periódico]
      It has been proposed that women had a higher migration rate than men throughout human evolutionary history. However, in a recent study of South American natives using mtDNA restriction fragment polymorphisms and Y-chromosome ...