Listar Ciencias Biologicas por tema "BDNF"
Mostrando ítems 1-7 de 7
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Cognitive development and brain gray matter susceptibility to prenatal adversities : moderation by the prefrontal cortex brain-derived neurotrophic factor gene co-expression network
(2021) [Artículo de periódico]Background: Previous studies focused on the relationship between prenatal conditions and neurodevelopmental outcomes later in life, but few have explored the interplay between gene co-expression networks and prenatal ... -
Differential neuroplastic changes in fibromyalgia and depression indexed by up-regulation of motor cortex inhibition and disinhibition of the descending pain system : an exploratory study
(2019) [Artículo de periódico]Background: Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption of neuroplastic processes that ... -
Higher serum S100b and BDNF levels are correlated with a lower pressure-pain threshold in fibromyalgia
(2014) [Artículo de periódico]Background: Fibromyalgia (FM) is conceptualized as a central sensitization (CS) condition, that presents high serum brain-derived neurotrophic factor (BDNF) and neuroglia activation. Although the S100B protein regulates ... -
Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia : a phase II, randomized, double-dummy, controlled trial
(2014) [Artículo de periódico]Background: Central disinhibition is a mechanism involved in the physiopathology of fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We hypothesized that treatment with melatonin alone or in ... -
Novel insights of effects of pregabalin on neural mechanisms of intracortical disinhibition in physiopathology of fibromyalgia : an explanatory, randomized, double-blind crossover study
(2018) [Artículo de periódico]The fibromyalgia (FM) physiopathology involves an intracortical excitability/inhibition imbalance as measured by transcranial magnetic stimulation measures (TMS). TMS measures provide an index that can help to understand ... -
Perisynaptic astrocytes as a potential target for novel antidepressant drugs
(2021) [Artículo de periódico]Emerging evidence suggests that dysfunctions in glutamatergic signaling are associated with the pathophysiology of depression. Several molecules that act on glutamate binding sites, so-called glutamatergic modulators, are ... -
The fear of pain questionnaire : psychometric properties of a Brazilian version for adolescents and its relationship with brain-derived neurotrophic factor (BDNF)
(2019) [Artículo de periódico]Objectives: The primary aim was to assess the psychometric properties (including internal consistency, construct validity, criterion validity, criterion-group validity and responsiveness) of the Fear of Pain Questionnaire ...