Mostrando ítems 1122-1141 de 3051

    • Evolutionary plasticity determination by orthologous groups distribution 

      Dalmolin, Rodrigo Juliani Siqueira; Castro, Mauro Antônio Alves; Rybarczyk Filho, José Luiz; Souza, Luís Henrique Trentin de; Almeida, Rita Maria Cunha de; Moreira, Jose Claudio Fonseca (2011) [Artículo de periódico]
      Background: Genetic plasticity may be understood as the ability of a functional gene network to tolerate alterations in its components or structure. Usually, the studies involving gene modifications in the course of the ...
    • Evolutionary responses to a constructed niche: ancient mesoamericans as a model of gene-culture coevolution 

      Hunemeier, Tábita; Amorim, Carlos Eduardo Guerra; Azevedo, Soledad de; Contini, Veronica; Acunã Alonzo, Víctor; Rothhammer, Francisco; Dugoujon, Jean-Michel; Mazières, Stéphane; Barrantes, Ramiro; Villarreal Molina, Maria Teresa; Paixão Côrtes, Vanessa Rodrigues; Salzano, Francisco Mauro; Canizales-Quinteros, Samuel; Ruiz-Linares, Andres; Bortolini, Maria Cátira (2012) [Artículo de periódico]
      Culture and genetics rely on two distinct but not isolated transmission systems. Cultural processes may change the human selective environment and thereby affect which individuals survive and reproduce. Here, we evaluated ...
    • Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis 

      Zolet, Andreia Carina Turchetto; Maraschin, Felipe dos Santos; Morais, Guilherme Loss de; Cagliari, Alexandro; Andrade, Claudia Marlise Balbinotti; Margis-Pinheiro, Márcia; Margis, Rogerio (2011) [Artículo de periódico]
      Background: Triacylglycerides (TAGs) are a class of neutral lipids that represent the most important storage form of energy for eukaryotic cells. DGAT (acyl-CoA: diacylglycerol acyltransferase; EC 2.3.1.20) is a transmembrane ...
    • Evolution of DNMT2 in drosophilids: evidence for positive and purifying selection and insights into new protein (pathways) interactions 

      Vieira, Gilberto Cavalheiro; D'Ávila, Marícia Fantinel; Zanini, Rebeca; Deprá, Maríndia; Gaiesky, Vera Lúcia da Silva Valente (2018) [Artículo de periódico]
      The DNA methyltransferase 2 (DNMT2) protein is the most conserved member of the DNA methyltransferase family. Nevertheless, its substrate specificity is still controversial and elusive. The genomic role and determinants ...
    • Evolution of the spontaneous sourdoughs microbiota prepared with organic or conventional whole wheat flours from South Brazil 

      Costa, Letícia da Fontoura Xavier; Kothe, Caroline Isabel; Grassotti, Tiela Trapp; Garske, Raquel Pischke; Sandoval, Beatriz Nagel; Varela, Ana Paula Muterle; Prichula, Janira; Frazzon, Jeverson; Mann, Michele Bertoni; Thys, Roberta Cruz Silveira; Frazzon, Ana Paula Guedes (2022) [Artículo de periódico]
      The purpose of this study was to compare the composition and stability of bacteria and fungi communities during the propagation of sourdoughs prepared with organic or conventional whole wheat (Triticum aestivum) flours ...
    • Existe uma associação entre mortalidade por câncer e uso de agrotóxicos? Uma contribuição ao debate 

      Jobim, Paulo Fernandes Costa; Nunes, Luciana Neves; Giugliani, Roberto; Cruz, Ivana Beatrici Manica da (2010) [Artículo de periódico]
      O uso crônico de agrotóxicos em regiões rurais no Estado do Rio Grande do Sul (RS) tem sido tentativamente relacionado a um possível aumento na incidência de câncer nos trabalhadores rurais. Foi realizado um estudo ecológico ...
    • Exome chip analyses in adult attention deficit hyperactivity disorder 

      Zayats, Tetyana; Schneider, Sarah Kittel; Ribasés, Marta; Mota, Nina Roth; Grevet, Eugenio Horácio; Arias Vasquez, Alejandro; Breen, Gerome; Bau, Claiton Henrique Dotto; Buitelaar, Jan K.; Haavik, Jan; Johansson, Stefan (2016) [Artículo de periódico]
      Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ...
    • Exosomes for HIV treatment: some advances and perspectives 

      Veit, Tiago Degani; Ellwanger, Joel Henrique; Chies, Jose Artur Bogo (2022) [Artículo de periódico]
      Resumo não disponível
    • Exosomes : small EVs with large immunomodulatory effect in glioblastoma 

      Benecke, Laura; Coray, Mali; Umbricht, Sandra; Chiang, Dapi; Figueiró, Fabrício; Muller, Laurent (2021) [Artículo de periódico]
      Glioblastomas are among the most aggressive tumors, and with low survival rates. They are characterized by the ability to create a highly immunosuppressive tumor microenvironment. Exosomes, small extracellular vesicles ...
    • Experience of the NPC Brazil network with a comprehensive program for the screening and diagnosis of Niemann-Pick disease type C 

      Kubaski, Francyne; Burlina, Alberto; Polo, Giulia; Pereira, Danilo; Herbst, Zackary M.; Silva, Camilo; Trapp, Franciele Barbosa; Tirelli, Kristiane Michelin; Lopes, Franciele Fátima; Burin, Maira Graeff; Facchin, Ana Carolina Brusius; Netto, Alice Brinckmann Oliveira; Faqueti, Larissa Gabriela; Iop, Gabrielle Dineck; Poletto, Édina; Giugliani, Roberto (2022) [Artículo de periódico]
      Niemann-Pick disease type C (NPC) is a lysosomal disorder caused by impaired cholesterol metabolism. Levels of lysosphingomyelin 509 (LysoSM509) have been shown elevated in dried blood spots (DBS) of NPC and acid ...
    • Uma experiência terapêutica no manejo da doença da urina do xarope do bordo 

      Jardim, Laura Bannach; Martins, Carlos; Pires, Ricardo Flores; Sanseverino, Maria Teresa Vieira; Refosco, Lilia Farret; Vieira, Rita de Cassia; Trotta, Eliana de Andrade; Vargas, Carmen Regla; Camargo Neto, Eurico; Giugliani, Roberto (1995) [Artículo de periódico]
      Relata-se aqui o manejo terapêutico realizado em um paciente portador da Doença da Urina do Xarope de Bordo, com diagnóstico e encaminhamento tardios (2 e 5 meses). Uma vez que o paciente apresentava níveis extremamente ...
    • Experimental infection of rabbits with a recombinant bovine herpesvirus type 5 (BoHV-5) gI, gE and US9-negative 

      Silva, Alessandra D'Avila da; Franco, Ana Claudia; Esteves, Paulo Augusto; Spilki, Fernando Rosado; Roehe, Paulo Michel (2009) [Artículo de periódico]
      O herpesvírus bovino tipo 5 é uma das principais causas de meningoencefalite viral em bovinos. A expressão de diferentes proteínas virais tem sido associada à neuropatogenia do BoHV-5. Entre estas, a gI, gE e US9 têm sido ...
    • Experimental model of gene transfection in healthy canine myocardium. Perspectives of gene therapy for ischemic heart disease 

      Kalil, Renato Abdala Karam; Teixeira, Leonardo Augusto Karam; Mastalir, Eduardo T.; Moreno, Paulo Lavaniere de Azevedo; Fricke, Cecilia Helena; Nardi, Nance Beyer (2002) [Artículo de periódico]
      Objective - To assess the transfection of the gene that encodes green fluorescent protein (GFP) through direct intramyocardial injection. Methods - The pREGFP plasmid vector was used. The EGFP gene was inserted downstream ...
    • Expert range maps of global mammal distributions harmonised to three taxonomic authorities 

      Marsh, Charles J.; Sica, Yanina V.; Del Toro Mijares, Isabel; Ranipeta, Ajay; Torselli, Michael A.; Wilson, Don E.; Aguirre, Luís Fernando; Moraes, Diego Astúa de; Baker, Andrew M.; Chiquito, Elisandra De Almeida; Freitas, Thales Renato Ochotorena de; Leite, Yuri Luiz Reis; Pavan, Ana Carolina; Queiroz, Helder L.; Talebi, Mauricio; Tirira, Diego G.; Upham, Nathan S.; Jetz, Walter (2022) [Artículo de periódico]
      Aim: Comprehensive, global information on species' occurrences is an essential biodiversity variable and central to a range of applications in ecology, evolution, biogeography and conservation. Expert range maps often ...
    • Explorando a bacia hidrográfica na escola : contribuições à educação ambiental 

      Bergmann, Melissa; Pedrozo, Catarina da Silva (2008) [Artículo de periódico]
      Este trabalho foi desenvolvido em duas escolas públicas do município de Giruá, RS, com a participação de professores e estudantes dos Ensinos Fundamental e Médio, com ênfase na sub-bacia do Rio Santo Cristo. Os procedimentos ...
    • Exploration of the Yield Potential of Mesoamerican Wild Common Beans From Contrasting Eco-Geographic Regions by Nested Recombinant Inbred Populations 

      Mier y Teran, Jorge C. Berny; Konzen, Enéas Ricardo; Palkovic, Antonia; Tsai, Siu Mui; Gepts, Paul (2020) [Artículo de periódico]
      Genetic analyses and utilization of wild genetic variation for crop improvement in common bean (Phaseolus vulgaris L.) have been hampered by yield evaluation difficulties, identification of advantageous variation, and ...
    • Exploring CD39 and CD73 expression as potential biomarkers in prostate cancer 

      Gardani, Carla Fernanda Furtado; Pedrazza, Eduardo Luiz; Paz, Victória Santos; Zanirati, Gabriele Goulart; Costa, Jaderson Costa da; Andrejew, Roberta; Ulrich, Henning; Scholl, Juliete Nathali; Figueiró, Fabrício; Rockenbach, Liliana; Morrone, Fernanda Bueno (2023) [Artículo de periódico]
      Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading ...
    • Exploring facial thermography patterns in women with chronic migraine 

      Fracasso, Bruno Veloso; Castro, Renato Bender; Brioschi, Marcos Leal; Malysz, Tais (2023) [Artículo de periódico]
      (1) Background: Chronic migraine is a debilitating neurological condition affecting millions worldwide. This study delves into the facial point-of-care (POC) thermographic patterns of women with chronic migraine, aiming ...
    • Exploring potential impacts of pregnancy-related maternal immune activation and extracellular vesicles on immune alterations observed in autism spectrum disorder 

      Kaminski, Valéria de Lima; Michita, Rafael Tomoya; Ellwanger, Joel Henrique; Veit, Tiago Degani; Schuch, Jaqueline Bohrer; Riesgo, Rudimar dos Santos; Roman, Tatiana; Chies, Jose Artur Bogo (2023) [Artículo de periódico]
      Autism Spectrum Disorder (ASD) is a set of neurodevelopmental disorders usually observed in early life, with impacts on behavioral and social skills. Incidence of ASD has been dramatically increasing worldwide, possibly ...
    • Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas 

      Vieira, Igor Araújo; Viola, Guilherme Danielski; Pezzi, Eduarda Heidrich; Kowalski, Thayne Woycinck; Fernandes, Bruna Vieira; Andreis, Tiago Finger; Bom, Natascha; Sonnenstrahl, Giulianna; Rocha, Yasminne Marinho de Araújo; Corrêa, Bruno da Silveira; Donatti, Luiza Mezzomo; Sant'Anna, Gabriela dos Santos; Corleta, Helena von Eye; Brum, Ilma Simoni; Rosset, Clévia; Vianna, Fernanda Sales Luiz; Macedo, Gabriel S.; Palmero, Edenir Inêz; Prolla, Patrícia Ashton (2023) [Artículo de periódico]
      The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet ...