Browsing Biological Sciences by Title
Now showing items 1122-1141 of 3051
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Evolutionary plasticity determination by orthologous groups distribution
(2011) [Journal article]Background: Genetic plasticity may be understood as the ability of a functional gene network to tolerate alterations in its components or structure. Usually, the studies involving gene modifications in the course of the ... -
Evolutionary responses to a constructed niche: ancient mesoamericans as a model of gene-culture coevolution
(2012) [Journal article]Culture and genetics rely on two distinct but not isolated transmission systems. Cultural processes may change the human selective environment and thereby affect which individuals survive and reproduce. Here, we evaluated ... -
Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis
(2011) [Journal article]Background: Triacylglycerides (TAGs) are a class of neutral lipids that represent the most important storage form of energy for eukaryotic cells. DGAT (acyl-CoA: diacylglycerol acyltransferase; EC 2.3.1.20) is a transmembrane ... -
Evolution of DNMT2 in drosophilids: evidence for positive and purifying selection and insights into new protein (pathways) interactions
(2018) [Journal article]The DNA methyltransferase 2 (DNMT2) protein is the most conserved member of the DNA methyltransferase family. Nevertheless, its substrate specificity is still controversial and elusive. The genomic role and determinants ... -
Evolution of the spontaneous sourdoughs microbiota prepared with organic or conventional whole wheat flours from South Brazil
(2022) [Journal article]The purpose of this study was to compare the composition and stability of bacteria and fungi communities during the propagation of sourdoughs prepared with organic or conventional whole wheat (Triticum aestivum) flours ... -
Existe uma associação entre mortalidade por câncer e uso de agrotóxicos? Uma contribuição ao debate
(2010) [Journal article]O uso crônico de agrotóxicos em regiões rurais no Estado do Rio Grande do Sul (RS) tem sido tentativamente relacionado a um possível aumento na incidência de câncer nos trabalhadores rurais. Foi realizado um estudo ecológico ... -
Exome chip analyses in adult attention deficit hyperactivity disorder
(2016) [Journal article]Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ... -
Exosomes for HIV treatment: some advances and perspectives
(2022) [Journal article]Resumo não disponível -
Exosomes : small EVs with large immunomodulatory effect in glioblastoma
(2021) [Journal article]Glioblastomas are among the most aggressive tumors, and with low survival rates. They are characterized by the ability to create a highly immunosuppressive tumor microenvironment. Exosomes, small extracellular vesicles ... -
Experience of the NPC Brazil network with a comprehensive program for the screening and diagnosis of Niemann-Pick disease type C
(2022) [Journal article]Niemann-Pick disease type C (NPC) is a lysosomal disorder caused by impaired cholesterol metabolism. Levels of lysosphingomyelin 509 (LysoSM509) have been shown elevated in dried blood spots (DBS) of NPC and acid ... -
Uma experiência terapêutica no manejo da doença da urina do xarope do bordo
(1995) [Journal article]Relata-se aqui o manejo terapêutico realizado em um paciente portador da Doença da Urina do Xarope de Bordo, com diagnóstico e encaminhamento tardios (2 e 5 meses). Uma vez que o paciente apresentava níveis extremamente ... -
Experimental infection of rabbits with a recombinant bovine herpesvirus type 5 (BoHV-5) gI, gE and US9-negative
(2009) [Journal article]O herpesvírus bovino tipo 5 é uma das principais causas de meningoencefalite viral em bovinos. A expressão de diferentes proteínas virais tem sido associada à neuropatogenia do BoHV-5. Entre estas, a gI, gE e US9 têm sido ... -
Experimental model of gene transfection in healthy canine myocardium. Perspectives of gene therapy for ischemic heart disease
(2002) [Journal article]Objective - To assess the transfection of the gene that encodes green fluorescent protein (GFP) through direct intramyocardial injection. Methods - The pREGFP plasmid vector was used. The EGFP gene was inserted downstream ... -
Expert range maps of global mammal distributions harmonised to three taxonomic authorities
(2022) [Journal article]Aim: Comprehensive, global information on species' occurrences is an essential biodiversity variable and central to a range of applications in ecology, evolution, biogeography and conservation. Expert range maps often ... -
Explorando a bacia hidrográfica na escola : contribuições à educação ambiental
(2008) [Journal article]Este trabalho foi desenvolvido em duas escolas públicas do município de Giruá, RS, com a participação de professores e estudantes dos Ensinos Fundamental e Médio, com ênfase na sub-bacia do Rio Santo Cristo. Os procedimentos ... -
Exploration of the Yield Potential of Mesoamerican Wild Common Beans From Contrasting Eco-Geographic Regions by Nested Recombinant Inbred Populations
(2020) [Journal article]Genetic analyses and utilization of wild genetic variation for crop improvement in common bean (Phaseolus vulgaris L.) have been hampered by yield evaluation difficulties, identification of advantageous variation, and ... -
Exploring CD39 and CD73 expression as potential biomarkers in prostate cancer
(2023) [Journal article]Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading ... -
Exploring facial thermography patterns in women with chronic migraine
(2023) [Journal article](1) Background: Chronic migraine is a debilitating neurological condition affecting millions worldwide. This study delves into the facial point-of-care (POC) thermographic patterns of women with chronic migraine, aiming ... -
Exploring potential impacts of pregnancy-related maternal immune activation and extracellular vesicles on immune alterations observed in autism spectrum disorder
(2023) [Journal article]Autism Spectrum Disorder (ASD) is a set of neurodevelopmental disorders usually observed in early life, with impacts on behavioral and social skills. Incidence of ASD has been dramatically increasing worldwide, possibly ... -
Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas
(2023) [Journal article]The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet ...