Listar Ciencias Biologicas por título

Mostrando ítems 1889-1908 de 3039

    • N-acetylcysteine downregulates phosphorylated p-38 expression but does not reverse the increased superoxide anion levels in the spinal cord of rats with neuropathic pain 

      Horst, Andréa; Souza, Jéssica Araújo de; Santos, Maria do Carmo Quevedo; Riffel, Ana Paula Konzen; Kolberg, Carolina; Ribeiro, Maria Flavia Marques; Fraga, Luciano Sturmer de; Partata, Wania Aparecida (2017) [Artículo de periódico]
      We determined the effect of N-acetylcysteine (NAC) on the expression of the phosphorylated p38 (p-p38) protein and superoxide anion generation (SAG), two important players in the processing of neuropathic pain, in the ...

    • N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis 

      Gasparotto, Juciano; Kunzler, Alice; Senger, Mário Roberto; Souza , Celeste da Silva Freitas de; De Simone, Salvatore Giovanni; Bortolin, Rafael Calixto; Somensi, Nauana; Dal Pizzol, Felipe; Moreira, Jose Claudio Fonseca; Abreu Silva, Ana Lúcia; Calabrese, Katia da Silva; Silva Junior, Floriano Paes; Gelain, Daniel Pens (2017) [Artículo de periódico]
      BACKGROUND Leishmaniasis is a parasitosis caused by several species of the genus Leishmania. These parasites present high resistance against oxidative stress generated by inflammatory cells. OBJECTIVES To investigate ...

    • N-Acetylcysteine micronization by the seds technique using supercritical CO2 

      Aguiar, Gean Pablo Silva; Chaves, Lorenzo Matteo Pereira Corá de; Boschetto, Daiane Lúcia; Piato, Angelo Luis Stapassoli; Oliveira, Jose Vladimir de; Lanza, Marcelo (2018) [Artículo de periódico]
      Abstract - N-Acetylcysteine (NAC) is a thiol (-SH) with a strong antioxidant activity. This compound has demonstrated positive effects on chronic kidney disease, cancer, pulmonary insufficiency and other diseases. The aim ...

    • N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae 

      Benvenutti, Radharani; Marcon, Matheus Felipe; Reis, Carlos Guilherme Rosa; Nery, Laura Roesler; Miguel, Camila; Herrmann, Ana Paula; Vianna, Monica Ryff Moreira Roca; Piato, Angelo Luis Stapassoli (2018) [Artículo de periódico]
      Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder. In addition to its highly debilitating motor symptoms, non-motor symptoms may precede their motor counterparts by many years, which ...

    • Nanobacteria-like particles : a threat to cell cultures 

      Simonetti, Amauri Braga; Hidalgo, Gelsa Edith Navarro; Campos, Karen; Mergener, Michelle; David, Cintia de; Oliveira, Anna Paula de; Roehe, Paulo Michel (2007) [Artículo de periódico]
      The main goal of this study is to alert researchers who work with cell cultures for the risk of contamination by structures called nanobacteria (NB). NB are tiny structures with size varying from 80 to 500 nm, commonly ...

    • Nanoemulsion improves the antifungal activity of allylic thiocyanates against yeasts and filamentous pathogenic fungi 

      Dalla Lana, Daiane Flores; Giuliani, Laura Minussi; Reoleon, Jéssica Brandão; Lopes, William; Vainstein, Marilene Henning; Danielli, Letícia Jacobi; Bergamo, Vanessa Zafaneli; Pippi, Bruna; Appel, Miriam Angela Marchi; Teixeira, Mário Lettieri; Oliveira, Luis Flávio Souza de; Machado, Michel Mansur; Andrade, Saulo Fernandes de; Sá, Marcus Mandolesi; Ferreira, Misael; Munaretto, Laiéli dos Santos; Cruz, Letícia; Silveira, Gustavo Pozza; Silva, Edilma Elayne da; Fuentefria, Alexandre Meneghello (2018) [Artículo de periódico]
      We report the antifungal and antichemotactic activities of a series of allylic thiocyanates with low toxicity. We also show improved antifungal activity of the most promising compound when used in a nanoemulsion (NE). The ...

    • Nanoformulation shows cytotoxicity against glioblastoma cell lines and antiangiogenic activity in chicken chorioallantoic membrane 

      Dallemole, Danieli Rosane; Terroso, Thatiana Ferreira; Alves, Aline de Cristo Soares; Scholl, Juliete Nathali; Onzi, Giovana Ravizzoni; Cé, Rodrigo; Paese, Karina; Battastini, Ana Maria Oliveira; Guterres, Silvia Stanisçuaski; Figueiró, Fabrício; Pohlmann, Adriana Raffin (2021) [Artículo de periódico]
      Glioblastoma (GB) is a histological and genetically heterogeneous brain tumor that is highly proliferative and vascularized. The prognosis is poor with currently available treatment. In this study, we evaluated the ...

    • Naringin supplementation during pregnancy induces sex and region-specific alterations in the offspring’s brain redox status 

      Santos, Bernardo Gindri dos; Klein, Caroline Peres; Crestani, Mariana Scortegagna; Maurmann, Rafael Moura; Hözer, Régis Mateus; Rodrigues, Karoline dos Santos; August, Pauline Maciel; Matté, Cristiane (2021) [Artículo de periódico]
      Research has shown the beneficial effects of naringin supplementation to adult rodents, which can ameliorate oxidative stress in disease models. However, evidence has demonstrated that polyphenol supplementation induced ...

    • National Science and Technology Institute for Translational Medicine (INCT-TM) : advancing the field of translational medicine and mental health 

      Hallak, Jaime Eduardo Cecilio; Crippa, José Alexandre de Souza; Quevedo, João Luciano de; Roesler, Rafael; Schroder, Nadja; Nardi, Antonio Egidio; Kapczinski, Flávio Pereira (2010) [Artículo de periódico]
      Objetivo: Medicina translacional pode ser descrita como a aplicação integrada de ferramentas farmacológicas inovadoras, biomarcadores, métodos e tecnologias clínicas e delineamentos de pesquisa para aumentar o conhecimento ...

    • Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population 

      Romero Hidalgo, Sandra; Bortolini, Maria Cátira; Granados, Julio; Corona, Teresa (2020) [Artículo de periódico]
      Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the admixture between mainly Native American and European populations, ...

    • Natural enemies of the Gall-maker Eugeniamyia dispar (Diptera, Cecidomyiidae): predatory ants and parasitoids 

      Mendonça Junior, Milton de Souza; Romanowski, Helena Piccoli (2002) [Artículo de periódico]
      Natural enemies of the gall maker Eugeniamyia dispar (Diptera: Cecidomyiidae) were studied on the urban area of Porto Alegre, RS, Brazil from October 1993 to March 1996. Galls and associated arthropods were followed weekly ...

    • Natural plant alkaloid (Emetine) inhibits HIV-1 replication by interfering with reverse transcriptase activity. 

      Valadão, Ana Luiza Chaves; Abreu, Celina Monteiro; Dias, Juliana Zanatta; Arantes, Pablo Ricardo; Verli, Hugo; Tanuri, Amilcar; Aguiar, Renato Santana (2015) [Artículo de periódico]
      Ipecac alkaloids are secondary metabolites produced in the medicinal plant Psychotria ipecacuanha. Emetine is the main alkaloid of ipecac and one of the active compounds in syrup of Ipecac with emetic property. Here we ...

    • Nature of insoluble material found in the bottom of soybean biodiesel storage tank : chemical and microbiological approach 

      Cazarolli, Juciana Clarice; Boelter, Gabriela; Lima, Amanda Muliterno Domingues Lourenço de; Hengles, Thaisa Concha Vasquez; Correa, Camila; Peralba, Maria do Carmo Ruaro; Ferrão, Marco Flôres; Cavalcanti, Eduardo Homem de Siqueira; Bisol, Márcia Veroneze; Bezerra, Kelly da Silva; Antoniosi Filho, Nelson Roberto; Bento, Fatima Menezes (2018) [Artículo de periódico]
      During biodiesel storage, chemical reactions may occur, producing sludges. The aim of this study was to characterize the chemical and microbial composition of the sludge found in a biodiesel storage tank. The material was ...

    • Neoadjuvant multikinase inhibitor in patients with locally advanced unresectable thyroid carcinoma 

      Nava, Carla Fernanda; Scheffel, Rafael Selbach; Cristo, Ana Patrícia de; Vargas, Carla Vaz Ferreira; Weber, Shana de Souto; Zanella, André Borsatto; Paixão, Francisco Costa; Guimaraes, Jose Ricardo; Graudenz, Márcia Silveira; Dora, José Miguel Silva; Maia, Ana Luiza Silva (2019) [Artículo de periódico]
      Background: Papillary thyroid carcinoma (PTC) is the most common and less aggressive thyroid cancer, but some patients may display locally advanced disease. Therapeutic options are limited in these cases, particularly for ...

    • Neonatal handling and the expression of immunoreactivity to tyrosine hydroxylase in the hypothalamus of adult male rats 

      Hermel, Erica do Espirito Santo; Severino, Gabriela Sentena; Cecconello, Ana Lúcia; Pereira, Francine Martins; Sanvitto, Gilberto Luiz; Lucion, Aldo Bolten (2001) [Artículo de periódico]
      Neonatal handling has long-lasting effects on behavior and stress reactivity. The purpose of the present study was to investigate the effect of neonatal handling on the number of dopaminergic neurons in the hypothalamic ...

    • Neonatal handling induces anovulatory estrous cycles in rats 

      Gomes, C. M.; Frantz, P.J.; Sanvitto, Gilberto Luiz; Franci, Janete Aparecida Anselmo; Lucion, Aldo Bolten (1999) [Artículo de periódico]

    • Neonatal interventions differently affect maternal care quality and have sexually dimorphic developmental effects on corticosterone secretion 

      Pereira, Natividade de Sá Couto; Ferreira, Charles Francisco; Lampert, Carine; Arcego, Danusa Mar; Toniazzo, Ana Paula; Bernardi, Juliana Rombaldi; Silva, Diego Carrilho da; Toigo, Eduardo von Poser; Diehl, Luisa Amalia; Krolow, Rachel; Silveira, Patrícia Pelufo; Dalmaz, Carla (2016) [Artículo de periódico]

    • Neonatal screening for congenital adrenal hyperplasia in Southern Brazil : a population based study with 108,409 infants 

      Kopacek, Cristiane; Castro, Simone Martins de; Prado, Mayara Jorgens; Silva, Cláudia Maria Dornelles da; Beltrão, Luciana Amorim; Spritzer, Poli Mara (2017) [Artículo de periódico]
      Background: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder associated with inborn errors of steroid metabolism. 21-hydroxylase enzyme deficiency occurs in 90 to 95% of all cases of CAH, with ...

    • Neonatal screening for four lysosomal storage diseases with a digital microfluidics platform: initial results in Brazil 

      Camargo Neto, Eurico; Schulte, Jaqueline; Pereira, Jamile Queiroz; Villalta, Heydy Varinia Bravo; Sampaio Filho, Claudio Augusto; Giugliani, Roberto (2018) [Artículo de periódico]
      We describe the initial results of a neonatal screening program for four lysosomal storage diseases (MPS I, Pompe, Gaucher and Fabry) using the digital microfluidics methodology. The method successfully identified patients ...

    • Neonatal screening for MPS disorders in Latin America : a survey of pilot initiatives 

      Kubaski, Francyne; Sousa, Inês; Amorim, Tatiana; Pereira, Danilo; Trometer, Joe; Souza, Alexandre; Ranieri, Enzo; Polo, Giulia; Burlina, A.; Facchin, Ana Carolina Brusius; Netto, Alice Brinckmann Oliveira; Tomatsu, Shunji; Giugliani, Roberto (2020) [Artículo de periódico]
      Newborn screening enables the diagnosis of treatable disorders at the early stages, and because of its countless benefits, conditions have been continuously added to screening panels, allowing early intervention, aiming ...