Mostrando ítems 1675-1694 de 3025

    • Lithium and methylphenidate : opposite effects on perirenal brown fat 

      Oliveira, José Menna; Crema, Leonardo Machado; Diehl, Luisa Amalia; Pettenuzzo, Letícia Ferreira; Bertinetti, Liane Tavares; Dalmaz, Carla; Rocha, Elizabete Rocha da (2010) [Artículo de periódico]
      Objetivo: Avaliar como a administração de lítio afeta o tecido adiposo marrom (perirrenal) e branco (inguinal) e se o metilfenidato modula os efeitos do lítio. Métodos: Vinte e cinco ratos Wistar adultos machos foram ...
    • Litoral norte do estado do Rio Grande do Sul : indicadores socioeconômicos e principais problemas ambientais 

      Moura, Nina Simone Vilaverde; Strohaecker, Tania Marques; Gruber, Nelson Luiz Sambaqui; Kunst, Aline Vicente; Ferreira, Anelise Helm (2006) [Artículo de periódico]
      A região do Litoral Norte, um dos segmentos da Zona Costeira do Rio Grande do Sul, distingue-se pela seqüência de ambientes longitudinais à costa. Após a área de interface com o mar, identifica-se uma planície sedimentar ...
    • Litter reduction during beach closure in the context of the COVID-19 pandemic : quantifying the impact of users on beach litter generation 

      Souza Filho, José Rodrigues de; Chagas, Antônio Anselmo Silva; Silva, Iracema Reimão; Guimarães, Junia Kacenelenbogen; Sakanaka, Tania Emi; Andrade Neto, Gerson Fernandino de (2023) [Artículo de periódico]
      This study aimed to quantify marine litter before and during the COVID pandemic found on urban touristic beaches closed to beachgoer access in northeastern Brazil. Litter identification and quantification was conducted ...
    • Liver glutathione depletion after preservation and reperfusion in human liver transplantation 

      Grezzana Filho, Tomáz de Jesus Maria; Corso, Carlos Otavio; Zanotelli, Maria Lucia; Marroni, Claudio Augusto; Brandao, Ajacio Bandeira de Mello; Schlindwein, Eduardo S.; Leipnitz, Ian; Meine, Mario Henrique Mendes de Mattos; Fleck Júnior, Alfeu de Medeiros; Hoppen, Ricardo Antônio; Kiss, Guilhermo; Cantisani, Guido Pio Gracco (2006) [Artículo de periódico]
      Purpose: The oxidative stress is an important mechanism responsible for dysfunction after orthotopic liver transplantation (OLT). Glutathione (GSH) low levels after cold storage render the grafts vulnerable to reperfusion ...
    • Liver involvement in patients with Gaucher disease types I and III 

      Starosta, Rodrigo Tzovenos; Vairo, Filippo Pinto e; Dornelles, Alícia Dorneles; Basgalupp, Suelen Porto; Siebert, Marina; Pedroso, Maria Lúcia Alves; Cerski, Carlos Thadeu Schmidt; Álvares-da-Silva, Mário Reis; Schwartz, Ida Vanessa Doederlein (2020) [Artículo de periódico]
      Background & aims Gaucher disease (GD) is a multisystemic disease. Liver involvement in GD is not well characterised and ranges from hepatomegaly to cirrhosis and hepatocellular carcinoma. We aim to describe, and assess ...
    • Lobos audazes 

      Silva, Carlos Eugenio (2023) [Artículo de periódico]
    • Local and regional drivers of ant communities in forest-grassland ecotones in South Brazil: a taxonomic and phylogenetic approach 

      Dröse, William; Podgaiski, Luciana Regina; Dias, Camila Fagundes; Mendonça Junior, Milton de Souza (2019) [Artículo de periódico]
      Understanding biological community distribution patterns and their drivers across different scales is one of the major goals of community ecology in a rapidly changing world. Considering natural forest-grassland ecotones ...
    • Localization and function of Rhipicephalus (Boophilus) microplus vitellin-degrading cysteine endopeptidase 

      Seixas, Adriana; Estrela, Andreia Bergamo; Ceolato, Juliana Casagrande; Pontes, Emerson Guedes; Lara, Flávio Alves; Gondim, Katia Calp; Termignoni, Carlos (2010) [Artículo de periódico]
      The tick Rhipicephalus (Boophilus) microplus is an important parasite of cattle in many areas of the tropics. Characterization of molecules involved in mechanisms such as vitellogenesis and embryo development may contribute ...
    • Localization of acid phosphatase activity on the testis of two teleostean species (Oreochromis niloticus and Odonthestes perugiae) 

      Garrido, Marilene Porawski; Wassermann, Guillermo Federico; Achaval-Elena, Matilde (2004) [Artículo de periódico]
      A atividade da fosfatase ácida (AcP) foi estudada em duas espécies de teleósteos em duas estações: verão e inverno. A atividade AcP foi detectada em células de Sertoli de tilápia (Oreochromis niloticus) somente durante o ...
    • Longer cortical silent period length is associated to binge eating disorder : an exploratory study 

      Antunes, Luciana da Conceição; Elkfury, Jéssica Lorenzzi; Parizotti, Cristiane Schulz; Brietzke, Aline Patrícia; Bandeira, Janete Shatkoski; Torres, Iraci Lucena da Silva; Fregni, Felipe; Caumo, Wolnei (2020) [Artículo de periódico]
      Introduction: Although binge eating disorder (BED) is an eating disorder and obesity is a clinical disease, it is known that both conditions present overlapped symptoms related to, at least partially, the disruption of ...
    • Long-lasting anxiolytic effect of neural precursor cells freshly prepared but not neurosphere-derived cell transplantation in newborn rats 

      Romariz, Simone Amaro Alves; Paiva, Daisyléa de Souza; Valente, Maria Fernanda; Barnabé, Gabriela Filoso; Frussa-Filho, Roberto; Silva, Regina Cláudia Barbosa da; Calcagnotto, Maria Elisa; Longo, Beatriz Monteiro (2014) [Artículo de periódico]
      Background: The GABAergic system plays an important role in modulating levels of anxiety. When transplanted into the brain, precursor cells from the medial ganglionic eminence (MGE) have the ability to differentiate into ...
    • Long-term ecological research in southern Brazil grasslands: effects of grazing exclusion and deferred grazing on plant and arthropod communities 

      Ferreira, Pedro Maria de Abreu; Andrade, Bianca Ott; Podgaiski, Luciana Regina; Dias, Amanda Camara; Pillar, Valerio de Patta; Overbeck, Gerhard Ernst; Mendonça Junior, Milton de Souza; Boldrini, Ilsi Iob (2020) [Artículo de periódico]
      Grazing exclusion may lead to biodiversity loss and homogenization of naturally heterogeneous and species-rich grassland ecosystems, and these effects may cascade to higher trophic levels and ecosystem properties. Although ...
    • Long-term follow-up of renal function in patients treated with migalastat for Fabry disease 

      Bichet, Daniel G.; Torra, Roser; Wallace, Eric; Hughes, Derralynn A.; Giugliani, Roberto; Skuban, Nina; Krusinska, Eva; Feldt-Rasmussen, Ulla; Schiffmann, Raphael; Nicholls, Kathy (2021) [Artículo de periódico]
      The effect of migalastat on long-term renal outcomes in enzyme replacement therapy (ERT)–naive and ERTexperienced patients with Fabry disease is not well defined. An integrated posthoc analysis of the phase 3 clinical ...
    • Long-term galsufase treatment associated with improved survival of patients with mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome) : 15-year follow-up from the survey study 

      Quartel, Adrian; Harmatz, Paul; Lampe, Christina; Guffon, Nathalie; Ketteridge, David; Teles, Elisa Leão; Jones, Simon A.; Giugliani, Roberto (2018) [Artículo de periódico]
      Mucopolysaccharidosis VI (MPS VI) is a progressive lysosomal storage disorder with multiorgan and multisystemic pathology. Currently, galsulfase enzyme replacement therapy (ERT) is the only approved treatment for MPS VI. ...
    • Long-term Landsat-based monthly burned area dataset for the Brazilian biomes using Deep Learning 

      Alencar, Ane Auxiliadora Costa; Arruda, Vera Laísa da Silva; Silva, Wallace Vieira da; Costa, Dhemerson Estevão Conciani da; Costa, Diego Pereira; Crusco, Natalia de Almeida; Duverger, Soltan Galano; Ferreira, Nilson Clementino; Rocha, Washington de Jesus Sant'Anna da Franca; Hasenack, Heinrich; Martenexen, Luiz Felipe Morais; Piontekowski, Valderli Jorge; Ribeiro, Noely Vicente; Rosa, Eduardo Reis; Rosa, Marcos Reis; Santos, Sarah Moura Batista dos; Shimbo, Julia Zanin; Vélez Martin, Eduardo (2022) [Artículo de periódico]
      Fire is a significant agent of landscape transformation on Earth, and a dynamic and ephemeral process that is challenging to map. Difficulties include the seasonality of native vegetation in areas affected by fire, the ...
    • Long-term outcomes of systemic therapies for Hurler syndrome : an international multicenter comparison 

      Eisengart, Julie B.; Rudser, Kyle D.; Xue, Yong; Orchard, Paul J.; Miller, Weston P.; Lund, Troy C.; Van Der Ploeg, Ans T.; Mercer, Jean; Jones, Simon A.; Mengel, Karl Eugen; Gökce, Seyfullah; Guffon, Nathalie; Giugliani, Roberto; Souza, Carolina Fischinger Moura de; Shapiro, Elsa G.; Whitley, Chester B. (2018) [Artículo de periódico]
      Purpose: Early treatment is critical for mucopolysaccharidosis type I (MPS I), justifying its incorporation into newborn screening. Enzyme replacement therapy (ERT) treats MPS I, yet presumptions that ERT cannot penetrate ...
    • Long-term outcomes with agalsidase alfa enzyme replacement therapy : analysis using deconstructed composite events 

      Beck, Michael; Hughes, Derralynn A.; Kampmann, Christoph; Pintos-Morell, G.; Ramaswami, Uma; West, Michael L.; Giugliani, Roberto (2017) [Artículo de periódico]
      This is a retrospective analysis of Fabry Outcome Survey data from children/adults (n =677) receiving agalsidase alfa enzyme replacement therapy for a median of 3 years, examining cerebrovascular, cardiac, and renal morbidity ...
    • Long-term reestablishment of alpha-L-iduronidase activity in MPS I fibroblasts after non-viral gene transfer 

      Poswar, Fabiano de Oliveira; Mayer, Fabiana Quoos; Burin, Maira Graeff; Matte, Ursula da Silveira; Giugliani, Roberto; Baldo, Guilherme (2017) [Artículo de periódico]
    • Lymphocytes from B-acute lymphoblastic leukemia patients present diferential regulation of the adenosinergic axis depending on risk stratifcation 

      Nunes, Vitoria Brum da Silva; Dias, Camila kehl; Scholl, Juliete Nathali; Sant' Ana, Alexia Nedel; Dias, Amanda de Fraga; Farias, Mariela Granero; Alegretti, Ana Paula; Sosnoski, Monalisa; Daudt, Liane Esteves; Michalowski, Mariana Bohns; Battastini, Ana Maria Oliveira; Paz, Alessandra Aparecida; Figueiró, Fabrício (2022) [Artículo de periódico]
      Purpose Although risk-stratifed chemotherapy regimens improve B-cell acute lymphoblastic leukemia (B-ALL) clinical outcome, relapse occurs in a signifcant number of cases. The identifcation of new therapeutic targets as ...
    • Lysosomal diseases : overview on current diagnosis and treatment 

      Poswar, Fabiano de Oliveira; Vairo, Filippo Pinto e; Burin, Maira Graeff; Tirelli, Kristiane Michelin; Facchin, Ana Carolina Brusius; Kubaski, Francyne; Souza, Carolina Fischinger Moura de; Baldo, Guilherme; Giugliani, Roberto (2019) [Artículo de periódico]
      Lysosomal diseases (LDs), also known as lysosomal storage diseases (LSDs), are a heterogeneous group of conditions caused by defects in lysosomal function. LDs may result from deficiency of lysosomal hydrolases, ...