• Rising rural body-mass index is the main driver of the global obesity epidemic in adults 

      Ezzati, Majid; Fuchs, Flávio Danni; Fuchs, Sandra Cristina Pereira Costa; Moreira, Leila Beltrami (2019) [Artigo de periódico]
      Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities. This has led to a widely reported view that urbanization is one of the most ...
    • Risk factors for infection with different hepatitis C virus genotypes in southern Brazil 

      Paraboni, Marisa Lucia Romani; Sbeghen, Marina Dallagasperina; Wolff, Fernando Herz; Moreira, Leila Beltrami (2012) [Artigo de periódico]
      Objectives. To investigate the proportion of different genotypes in countryside microregions in southern Brazil, and their association with risk factors. Methods. Cross-sectional study including a convenience sample of ...
    • Risks of long-term port use in enzyme replacement therapy for lysosomal storage disorders 

      Hendriksz, Christian J.; Harmatz, Paul; Giugliani, Roberto; Roberts, Jane T.; Arul, G. Suren (2017) [Artigo de periódico]
      Totally implantable vascular access devices (TIVADs) are commonly used in conjunction with enzyme replacement therapy (ERT) for lysosomal storage disorders (LSDs). This case series describes potential complications associated ...
    • Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder 

      Demontis, Ditte; Bau, Claiton Henrique Dotto; Grevet, Eugenio Horácio; Rohde, Luis Augusto Paim; Børglum, Anders Dupont (2021) [Artigo de periódico]
      Attention-Deficit/Hyperactivity Disorder (ADHD) is a childhood psychiatric disorder often comorbid with disruptive behavior disorders (DBDs). Here, we report a GWAS meta-analysis of ADHD comorbid with DBDs (ADHD + DBDs) ...
    • A role for adeno-associated viral vectors in gene therapy 

      Coura, Renata dos Santos; Nardi, Nance Beyer (2008) [Artigo de periódico]
      Gene therapy constitutes a therapeutic intervention based on modification of the genetic material of living cells, by correcting genetic defects or overexpressing therapeutic proteins. The success of gene therapy protocols ...
    • A role for neurotransmission and neurodevelopment in attention-deficit/hyperactivity disorder 

      Roman, Tatiana; Rohde, Luis Augusto Paim; Hutz, Mara Helena (2009) [Artigo de periódico]
      Attention-deficit/hyperactivity disorder (ADHD) has a moderate to high genetic component, probably due to many genes with small effects. Several susceptibility genes have been suggested on the basis of hypotheses that ...
    • Role of ferritin in the rice tolerance to iron overload 

      Silveira, Vivian Chagas da; Fadanelli, Cristina; Sperotto, Raul Antonio; Stein, Ricardo José; Basso, Luiz Augusto; Santos, Diogenes Santiago; Vaz Junior, Itabajara da Silva; Dias, Johnny Ferraz; Fett, Janette Palma (2009) [Artigo de periódico]
      Deficiência de ferro (Fe) ocorre freqüentemente em plantas, uma vez que este mineral é pouco disponível em condições aeróbicas. Plantas de arroz cultivadas sob alagamento, no entanto, estão sujeitas ao excesso de Fe, que ...
    • Role of gut microbiota in infectious and inflammatory diseases 

      Fiuza, Miriãn Ferrão Maciel; Müller, Guilherme Cerutti; Campos, Daniel Marques Stuart; Costa, Perpétua do Socorro Silva; Peruzzo, Juliano; Bonamigo, Renan Rangel; Veit, Tiago Degani; Vianna, Fernanda Sales Luiz (2023) [Artigo de periódico]
      Thousands of microorganisms compose the human gut microbiota, fighting pathogens in infectious diseases and inhibiting or inducing inflammation in different immunological contexts. The gut microbiome is a dynamic and complex ...
    • RT-PCR for detection on bovine parainfluenza virus type 3 (bPIV-3) 

      Vaucher, Rodrigo de Almeida; Simonetti, Amauri Braga; Roehe, Paulo Michel (2008) [Artigo de periódico]
      A técnica de RT-PCR tem sido freqüentemente utilizada para a detecção do vírus parainfluenza humano tipo 3 (hPIV- 3), mas a literatura é escassa em relação ao vírus parainfluenza bovino tipo 3 (bPIV-3) .O objetivo deste ...
    • Ruptured aneurysm in the posterior communicating segment of carotid artery presenting with contralateral oculomotor nerve palsy 

      Finger, Guilherme; Martins, Otávio Garcia; Nesi, William Mazzucco; Casarin, Mateus Carvalho; Almeida, Leandro Pelegrini de; Schiavo, Felipe Lourenzon; Santos, Samir Cezimbra dos; Stefani, Marco Antonio (2019) [Artigo de periódico]
      Background: Brain aneurysms are mostly discovered during the investigation of subarachnoid hemorrhage (SAH). Some patients present neurological signs that may suggest the aneurysm’s topography, and the oculomotor nerve ...
    • S100B protein related neonatal hypoxia 

      Martins, Régis Osório; Rotta, Newra Tellechea; Portela, Luis Valmor Cruz; Souza, Diogo Onofre Gomes de (2006) [Artigo de periódico]
      A participação de marcadores bioquímicos na avaliação de quadros de asfixia neonatal é cada vez mais relevante. A proteína S100B é de particular importância neste campo. O objetivo deste estudo foi procurar destacar a ...
    • Saccharomyces cerevisiae, a pérola dourada da microbiologia 

      Colombo, Mateus; Silva, Patrícia Valente da (2022) [Artigo de periódico]
    • Safeguarding human–wildlife cooperation 

      Van Der Waal, Jessica E. M.; Spottiswoode, Claire N.; Uomini, Natalie; Cantor, Mauricio; Daura-Jorge, Fábio Gonçalves; Afan, Anap I.; Attwood, Mairenn C.; Amphaeris, Jenny; Balasani, Fatima; Begg, Colleen M.; Blair, Cameron J.; Bronstein, Judith L.; Buanachique, Iahaia O.; Cuthill, Rion R. T.; Das, Jewel; Deb, Apurba; Dixit, Tanmay; Dlamini, Gcina S.; Dúnias, Edmond; Gedi, Isa I.; Gruber, Martin Jay; Hoffmann, Lilian Sander; Holzlehner, Tobias; Isack, Hussein A.; Laltaika, Eliupendo A.; Lloyd-Jones, David J.; Lund, Jess; Machado, Alexandre Marcel da Silva; Mahadevan, L.; Moreno, Ignacio Maria Benites; Nwaogu, Chima J.; Pereira, Valdomiro L.; Pierotti, Raymond; Rucunua, Seliano A.; Santos, Wilson F. dos; Serpa, Nathalia Barbosa; Smith, Brian D.; Tolkova, Irina; Tun, Tint; Pereira, João Victor Silva do Valle; Wood, Brian M.; Wrangham, Richard W.; Cram, Dominic L. (2022) [Artigo de periódico]
      Human–wildlife cooperation occurs when humans and free-living wild animals actively coordinate their behavior to achieve a mutually beneficial outcome. These interactions provide important benefits to both the human and ...
    • Safety of switching to Migalastat from enzyme replacement therapy in Fabry disease : experience from the Phase 3 ATTRACT study 

      Hughes, Derralynn A.; Nicholls, Kathleen M.; Sunder-Plassmann, G.; Jovanovic, Ana; Feldt-Rasmussen, Ulla; Schiffmann, Raphael; Giugliani, Roberto; Jain, Vipul; Viereck, Christopher; Castelli, Jeffrey P.; Skuban, Nina; Barth, Jay; Bichet, Daniel G. (2019) [Artigo de periódico]
    • Sales of "COVID kit" drugs and adverse drug reactions reported by the Brazilian Health Regulatory Agency 

      Lopes, Marina Hentschke; Botton, Mariana Rodrigues; Borges, Pâmella; Freitas, Martiela Vaz de; Mancuso, Aline Castello Branco; Matte, Ursula da Silveira (2022) [Artigo de periódico]
      Off-label use of azithromycin, hydroxychloroquine, and ivermectin (the "COVID kit") has been suggested for COVID-19 treatment in Brazil without clinical or scientific evidence of efficacy. These drugs have known adverse ...
    • Saliva de animais hematófagos : fonte de novos anticoagulantes 

      Ciprandi, Alessandra; Horn, Fabiana; Termignoni, Carlos (2003) [Artigo de periódico]
      Esta revisão tem como objetivo apresentar os anticoagulantes e inibidores da agregação plaquetária que foram encontrados em animais hematófagos. Esses animais precisam inibir as reações hemostáticas no local onde se alimentam ...
    • Salivary gland extract from Aedes aegypti improves survival in murine polymicrobial sepsis through oxidative mechanisms 

      Gomes, Rafaelli de Souza; Lima, Kely Campos Navegantes; Monteiro, Valter Vinícius Silva; Oliveira, Ana Lígia de Brito; Rodrigues, Dávila Valentina Silva; Reis, Jordano Ferreira; Gomes, Antonio Rafael Quadros; Prophiro, Josiane Somariva; Silva, Onilda Santos da; Romão, Pedro Roosevelt Torres; Estrada, Jorge Eduardo Chang; Monteiro, Marta Chagas (2018) [Artigo de periódico]
      Sepsis is a systemic disease with life-threatening potential and is characterized by a dysregulated immune response from the host to an infection. The organic dysfunction in sepsis is associated with the production of ...
    • Saliva, supragingival biofilm and root canals can harbor gene associated with resistance to lactamic agents 

      Moraes, Ludmila Coutinho; Parolo, Clarissa Cavalcanti Fatturi; Ferreira, Maria Beatriz Cardoso; Só, Marcus Vinicius Reis; Montagner, Francisco (2015) [Artigo de periódico]
      This study aimed to determine the presence of Prevotella strains and genes associated with resistance to lactamics in different oral niches from patients with/without primary endodontic infections. Saliva (S) and supragingival ...
    • O salto qualitativo em Theodosius Dobzhanky : unindo as tradições naturalista e experimentalista 

      Araujo, Aldo Mellender de (2001) [Artigo de periódico]
      Em alta durante quase todo o século XIX, o prestígio dos naturalistas caiu nas últimas décadas do mesmo século, na medida em que o enfoque dos estudos biológicos transitava do histórico para o funcional. A redescoberta dos ...
    • Salt resistance of interspecific crosses of domesticated and wild rice species 

      Wairich, Andriele; Wember, Louisa Sophie; Gassama, Lamin J; Wu, Lin-bo; Murugaiyan, Varunseelan; Ricachenevsky, Felipe Klein; Margis-Pinheiro, Márcia; Frei, Michael (2021) [Artigo de periódico]