Obesidade e o hipotálamo

Abstract

A obesidade é hoje um grande problema de saúde pública. Este artigo revisa o papel do hipotálamo na obesidade, em especial a dos neurônios NPY/AGRP, POMC/ CART, da área lateral e dos núcleos paraventricular e ventromedial do hipotálamo, e as conexões com a via corticolímbica.

Obesity is currently a major public health problem. This article reviews the role of the hypothalamus in obesity, with special reference to the NPY/AGRP and POMC/ CART neurons, located in the lateral hypothalamic area and in the paraventricular and ventromedial nuclei. We also review these neurons’ connections to the corticallimbic pathway.