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dc.contributor.authorVidor, Liliane Pintopt_BR
dc.contributor.authorTorres, Iraci Lucena da Silvapt_BR
dc.contributor.authorMedeiros, Liciane Fernandespt_BR
dc.contributor.authorSarria, Jairo Alberto Dussánpt_BR
dc.contributor.authorDall'Agnol, Letizziapt_BR
dc.contributor.authorDeitos, Alíciapt_BR
dc.contributor.authorBrietzke, Aline Patríciapt_BR
dc.contributor.authorLaste, Gabrielapt_BR
dc.contributor.authorRozisky, Joanna Ripollpt_BR
dc.contributor.authorFregni, Felipept_BR
dc.contributor.authorCaumo, Wolneipt_BR
dc.date.accessioned2015-02-14T02:19:06Zpt_BR
dc.date.issued2014pt_BR
dc.identifier.issn1471-2202pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/110151pt_BR
dc.description.abstractBackground: This study aimed to answer three questions related to chronic myofascial pain syndrome (MPS): 1) Is the motor cortex excitability, as assessed by transcranial magnetic stimulation parameters (TMS), related to state-trait anxiety? 2) Does anxiety modulate corticospinal excitability changes after evoked pain by Quantitative Sensory Testing (QST)? 3) Does the state-trait anxiety predict the response to pain evoked by QST if simultaneously receiving a heterotopic stimulus [Conditional Pain Modulation (CPM)]? We included females with chronic MPS (n = 47) and healthy controls (n = 11), aged 19 to 65 years. Motor cortex excitability was assessed by TMS, and anxiety was assessed based on the State-Trait Anxiety Inventory. The disability related to pain (DRP) was assessed by the Profile of Chronic Pain scale for the Brazilian population (B:PCP:S), and the psychophysical pain measurements were measured by the QST and CPM. Results: In patients, trait-anxiety was positively correlated to intracortical facilitation (ICF) at baseline and after QST evoked pain (β = 0.05 and β = 0.04, respectively) and negatively correlated to the cortical silent period (CSP) (β = -1.17 and β = -1.23, respectively) (P <0.05 for all comparisons). After QST evoked pain, the DRP was positively correlated to ICF (β= 0.02) (P < 0.05). Pain scores during CPM were positively correlated with trait-anxiety when it was concurrently with high DRP (β = 0.39; P = 0.02). Controls’ cortical excitability remained unchanged after QST. Conclusions: These findings suggest that, in chronic MPS, the imbalance between excitatory and inhibitory descending systems of the corticospinal tract is associated with higher trait-anxiety concurrent with higher DRP.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofBMC neuroscience. London. Vol. 15 (19 mar. 2014), 42 [13] p.pt_BR
dc.rightsOpen Accessen
dc.subjectAnsiedadept_BR
dc.subjectTranscranial magnetic stimulationen
dc.subjectChronic painen
dc.subjectSíndromes da dor miofascialpt_BR
dc.subjectNoninvasive brain stimulationen
dc.subjectEstimulação magnética transcranianapt_BR
dc.subjectNeuromodulationen
dc.subjectDor crônicapt_BR
dc.subjectAnxietyen
dc.subjectMyofascial pain syndromeen
dc.titleAssociation of anxiety with intracortical inhibition and descending pain modulation in chronic myofascial pain syndromept_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000915989pt_BR
dc.type.originEstrangeiropt_BR


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