Now showing items 1-10 of 10

    • Capsicumicine, a new bioinspired peptide from red peppers prevents staphylococcal biofilm in vitro and in vivo via a matrix anti-assembly mechanism of action 

      Von Borowski, Rafael Gomes; Chat, Sophie; Schneider, Rafael de Oliveira; Nonin-Lecomte, Sylvie; Bouaziz, Serge; Giudice, Emmanuel; Zimmer, Aline Rigon; Gnoatto, Simone Cristina Baggio; Macedo, Alexandre José; Gillet, Reynald (2021) [Journal article]
      Staphylococci are pathogenic biofilm-forming bacteria and a source of multidrug resistance and/or tolerance causing a broad spectrum of infections. These bacteria are enclosed in a matrix that allows them to colonize medical ...
    • Effects of zinc transporters on Cryptococcus gattii virulence 

      Schneider, Rafael de Oliveira; Padilha, Camila Diehl; Santos, Francine Melise dos; Piffer, Alicia Corbellini; Garcia, Ane Wichine Acosta; Kulmann, Marcos Iuri Roos; Schrank, Augusto; Silva, Lívia Kmetzsch Rosa e; Vainstein, Marilene Henning; Staats, Charley Christian (2015) [Journal article]
      Zinc is an essential nutrient for all living organisms because it is a co-factor of several important proteins. Furthermore, zinc may play an essential role in the infectiousness of microorganisms. Previously, we determined ...
    • Genes essenciais de cryptococcus 

      Rodrigues, Marcio Lourenço; Joffe, Luna Sobrino; Vainstein, Marilene Henning; Schrank, Augusto; Silva, Lívia Kmetzsch Rosa e; Staats, Charley Christian; Schneider, Rafael de Oliveira (2017) [Patent]
    • Homeostase de zinco na virulência de cryptococcus gattii e na interação com hospedeiro 

      Schneider, Rafael de Oliveira (2016) [Thesis]
      A imunidade nutricional é um importante mecanismo de defesa do hospedeiro. A mesma é caracterizada pela privação de nutrientes durante interação patógeno e hospedeiro, mostrando-se essencial tanto para eliminar quanto para ...
    • Metabolismo de zinco em Cryptococcus gattii : caracterização de mecanismos regulatórios de transporte 

      Schneider, Rafael de Oliveira (2012) [Dissertation]
      Cryptococcus gattii é uma levedura basidiomicética causadora da criptococose, doença que acomete diferentes órgãos de pacientes imunocompetentes, entre eles, pulmões, pele e sistema nervoso central. Durante o processo ...
    • Pathogenic diversity amongst serotype C VGIII and VGIV Cryptococcus gattii isolates 

      Rodrigues, Jéssica; Fonseca, Fernanda L.; Schneider, Rafael de Oliveira; Godinho, Rodrigo M. da C.; Firacative, Carolina; Maszewska, Krystyna; Meyer, Wieland; Schrank, Augusto; Staats, Charley Christian; Silva, Lívia Kmetzsch Rosa e; Vainstein, Marilene Henning; Rodrigues, Márcio L. (2015) [Journal article]
    • A plumieridine-rich fraction from Allamanda polyantha inhibits chitinolytic activity and exhibits antifungal properties against Cryptococcus neoformans 

      Souza, Eden Silva e; Barcellos, Vanessa de Abreu; Oliveira, Nicolau Sbaraini; Reuwsaat, Júlia Catarina Vieira; Schneider, Rafael de Oliveira; Silva, Adriana Corrêa da; Garcia, Ane Wichine Acosta; Von Poser, Gilsane Lino; Barbosa, Euzébio Guimarães; Lima, João Paulo Matos Santos; Vainstein, Marilene Henning (2020) [Journal article]
      Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules that are then deposited in the lungs. ...
    • Pseudonajide peptide derived from snake venom alters cell envelope integrity interfering on biofilm formation in Staphylococcus epidermidis 

      Schneider, Rafael de Oliveira; Barros, Muriel Primon de; Von Borowski, Rafael Gomes; Chat, Sophie; Nonin-Lecomte, Sylvie; Gillet, Reynald; Macedo, Alexandre José (2020) [Journal article]
      Background: The increase in bacterial resistance phenotype cases is a global health problem. New strategies must be explored by the scientific community in order to create new treatment alternatives. Animal venoms are a ...
    • Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells 

      Piffer, Alicia Corbellini; Santos, Francine Melise dos; Thomé, Marcos Paulo; Rosa, Camila Diehl da; Garcia, Ane Wichine Acosta; Kinskovski, Uriel Perin; Schneider, Rafael de Oliveira; Gerber, Alexandra Lehmkuhl; Feltes, Bruno César; Schrank, Augusto; Vasconcelos, Ana Tereza Ribeiro de; Lenz, Guido; Silva, Lívia Kmetzsch Rosa e; Vainstein, Marilene Henning; Staats, Charley Christian (2021) [Journal article]
      Cryptococcus neoformans and Cryptococcus gattii are the etiological agents of cryptococcosis, a high mortality disease. The development of such disease depends on the interaction of fungal cells with macrophages, in which ...
    • Zap1 regulates zinc homeostasis and modulates virulence in Cryptococcus gattii 

      Schneider, Rafael de Oliveira; Fogaça, Natully de Souza Süffert; Silva, Lívia Kmetzsch Rosa e; Schrank, Augusto; Vainstein, Marilene Henning; Staats, Charley Christian (2012) [Journal article]
      Zinc homeostasis is essential for fungal growth, as this metal is a critical structural component of several proteins, including transcription factors. The fungal pathogen Cryptococcus gattii obtains zinc from the stringent ...