Browsing by Author "Galera, Marcial Francis"

Now showing items 1-7 of 7

    • Association between Genetic Variants in NOS2 and TNF Genes with Congenital Zika Syndrome and Severe Microcephaly 

      Gomes, Julia do Amaral; Boquett, Juliano André; Silva, Juliana Herrero da; Galera, Marcial Francis; Andrade, Maria Denise Fernandes Carvalho de; Carvalho, Isabella Fernandes; Vianna, Fernanda Sales Luiz; Sgarioni, Eduarda; Trettel, Ana Cláudia Pereira Terças; Ribeiro, Bethânia de Freitas Rodrigues; Oliveira, Thalita Mara de; Faccini, Lavinia Schuler (2021) [Journal article]
      Zika virus (ZIKV) causes Congenital Zika Syndrome (CZS) in individuals exposed prenatally. Here, we investigated polymorphisms in VEGFA, PTGS2, NOS3, TNF, and NOS2 genes as risk factors to CZS. Forty children with CZS and ...

    • Cytogenomic integrative network analysis of the critical region associated with Wolf-Hirschhorn Syndrome 

      Corrêa, Thiago; Mergener, Rafaella; Leite, Júlio César Loguercio; Galera, Marcial Francis; Moreira, Lília Maria de Azevedo; Vargas, José Eduardo; Riegel, Mariluce (2018) [Journal article]
      Deletions in the 4p16.3 region are associated with Wolf-Hirschhorn syndrome (WHS), a contiguous gene deletion syndrome involving variable size deletions. In this study, we perform a cytogenomic integrative analysis combining ...

    • Functional polymorphisms in the p53 pathway genes on the genetic susceptibility to zika virus teratogenesis 

      Gomes, Julia do Amaral; Sgarioni, Eduarda; Vieira, Igor Araújo; Fraga, Lucas Rosa; Prolla, Patrícia Ashton; Terças, Ana Cláudia Pereira; Silva, Juliana Herrero da; Ribeiro, Bethânia de Freitas Rodrigues; Galera, Marcial Francis; Oliveira, Thalita Mara de; Carvalho, Maria Denise Fernandes; Carvalho, Isabella Fernandes; Faccini, Lavinia Schuler; Vianna, Fernanda Sales Luiz (2021) [Journal article]
      Congenital Zika Syndrome (CZS) occurs in up to 42% of individuals exposed to ZIKV prenatally. Deregulation in gene expression and protein levels of components of the p53 signaling pathway, such as p53 and MDM2, due to ZIKV ...

    • Gene interaction network analysis in Wolf-Hirschhorn Syndrome 

      Corrêa, Thiago; Mergener, Rafaella; Leite, Júlio César; Galera, Marcial Francis; Moreira, Lília Maria de Azevedo; Vargas, José Eduardo; Riegel, Mariluce (2017) [Abstract published in event]

    • Influência de variantes em genes da via de p53 na suscetibilidade à teratogênese do ZIKV 

      Sgarioni, Eduarda; Gomes, Julia do Amaral; Vieira, Igor Araújo; Terças, Ana Cláudia Pereira; Ribeiro, Bethânia de Freitas Rodrigues; Galera, Marcial Francis; Andrade, Maria Denise Fernandes Carvalho de; Faccini, Lavinia Schuler; Vianna, Fernanda Sales Luiz (2020) [Abstract published in event]

    • Mutations, clinical findings and survival estimates in South American patients with X-linked adrenoleukodystrophy 

      Pereira, Fernanda dos Santos; Matte, Ursula da Silveira; Habekost, Clarissa Troller; Castilhos, Raphael Machado de; El-Husny, Antonette Souto; Lourenço, Charles Marques; Vianna-Morgante, Angela M.; Giuliani, Liane de Rosso; Galera, Marcial Francis; Honjo, Raquel S.; Kim, Chong Ae; Politei, Juan Manuel; Vargas, Carmen Regla; Jardim, Laura Bannach (2012) [Journal article]
      In this study, we analyzed the ABCD1 gene in X-linked adrenoleukodystrophy (X-ALD) patients and relatives from 38 unrelated families from South America, as well as phenotypic proportions, survival estimates, and the potential ...

    • NOS2 e VEGFA como possíveis fatores de risco genéticos para a teratogênese do ZIKV em humanos 

      Gomes, Julia do Amaral; Sgarioni, Eduarda; Terças, Ana Cláudia Pereira; Ribeiro, Bethânia de Freitas Rodrigues; Galera, Marcial Francis; Andrade, Maria Denise Fernandes Carvalho de; Faccini, Lavinia Schuler; Vianna, Fernanda Sales Luiz (2020) [Abstract published in event]