Listar por tema "Transcriptional regulatory network reconstruction"

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Alzheimer's disease master regulators analysis : search for potential molecular targets and drug repositioning candidates

Vargas, Daiani Machado de; De Bastiani, Marco Antônio; Zimmer, Eduardo Rigon; Klamt, Fabio (2018) [Artículo de periódico]

Background: Alzheimer’s disease (AD) is a multifactorial and complex neuropathology that involves impairment of many intricate molecular mechanisms. Despite recent advances, AD pathophysiological characterization remains ...