Browsing by Subject "Disfunção cognitiva"
Now showing items 1-20 of 37
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Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia
(2021) [Journal article]Objective: To investigate the relationship between the topography of amyloid-β plaques, tau neurofibrillary tangles, and the overlap between the two, with cognitive dysfunction in individuals without dementia. Methods: We ... -
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload
(2018) [Journal article]Iron accumulation in the brain has been recognized as a common feature of both normal aging and neurodegenerative diseases. Cognitive dysfunction has been associated to iron excess in brain regions in humans. We have ... -
Associação dos níveis de BDNF (brain derived neurotrophic factor) no comprometimento cognitivo leve e na doença de Alzheimer
(2012) [Dissertation]Background: It has been suggested that there is an association between brain-derived neurotrophic factor (BDNF) and the neuropathology of Alzheimer’s disease (AD). However, little is known about the role of BDNF in subjects ... -
Associação dos níveis de BDNF com volume do hipocampo no comprometimento cognitivo leve e na doença de Alzheimer
(2016) [Thesis]Introdução: Perda de memória é um dos sintomas mais comuns em pacientes nos estágios iniciais da doença de Alzheimer; esses déficits são um reflexo do envolvimento da formação do hipocampo. O BDNF tem sido relacionado com ... -
Associação entre autopercepção auditiva e declínio cognitivo em idosos brasileiros : estudo populacional
(2021) [Work completion of graduation]Introdução: Saúde cognitiva é fator importante para qualidade de vida e autonomia dos idosos, sendo influenciada pela capacidade auditiva. Objetivo: Analisar a associação entre autopercepção auditiva e declínio cognitivo ... -
Association between descending pain modulatory system and cognitive impairment in fibromyalgia : a cross-sectional exploratory study
(2022) [Journal article]Background: The successful regulation of sensory input to the central nervous system depends on the descending pain modulatory system (DPMS). For the effective regulation of sensory input to the central nervous system and ... -
Avaliação da eficácia da dieta mind na prevenção de disfunções cognitivas : uma revisão sistemática
(2024) [Work completion of graduation]Resumo não disponível. -
Avaliação das proteínas astrogliais aquaporina-4, conexina-43 e Kir4.1 em um modelo de demência induzido por estreptozotocina
(2020) [Dissertation]O envelhecimento da população mundial vem se tornando uma das transformações sociais de maior significância do século XXI. Através dos danos moleculares e celulares resultantes do envelhecimento, a demência vem se tornando ... -
Avaliação do valor diagnóstico da escala de avaliação clínica da demência (CDR) utilizando o sistema de escore de soma das caixas para detecção de comprometimento cognitivo e demência
(2016) [Dissertation]Base teórica: Apesar de o escore da soma das caixas da escala de avaliação clínica da demência (CDR-SB) ser amplamente utilizado, sua aplicabilidade na avaliação do estadiamento da gravidade da demência e sua acurária para ... -
Brain-derived neurotrophic factor serum levels and hippocampal volume in mild cognitive impairment and dementia due to Alzheimer disease
(2016) [Journal article]Background/Aims: Hippocampal atrophy is a recognized biomarker of Alzheimer disease (AD) pathology. Serum brain-derived neurotrophic factor (BDNF) reduction has been associated with neurodegeneration. We aimed to evaluate ... -
Cognitive clusters in first-episode psychosis
(2021) [Journal article]Impairments in a broad range of cognitive domains have been consistently reported in some individuals with first-episode psychosis (FEP). Cognitive deficits can be observed during the prodromal stage. However, the course ... -
Comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats
(2020) [Journal article]Clinical studies show that physical exercise has anxiolytic and pro-cognitive properties for both healthy individuals and psychiatric patients. Most of these data refer to the effects of aerobic exercise. However, other ... -
Disfunção cognitiva em cães : revisão de literatura
(2020) [Work completion of graduation]A Síndrome da Disfunção Cognitiva Canina (SDCC) é uma alteração neurodegenerativa que afeta cães geriátricos, com idade geralmente acima de sete anos. A síndrome caracteriza-se por manifestações clínicas que são influenciadas ... -
Editorial : the impacts of iron accumulation on cognitive impairments
(2023) [Introductory and closing remarks] -
Efeitos do exercício físico combinado nas aptidões físicas não aeróbicas e cognitivas de indivíduos com transtorno por uso de álcool
(2023) [Work completion of specialization]Introdução: O transtorno por uso de álcool é complexo e demanda uma série de abordagens terapêuticas para melhora do quadro clínico e psiquiátrico. Indivíduos dependentes de álcool enfrentam ao longo de suas vidas agravos ... -
Effects of single low dose of dexamethasone before noncardiac and nonneurologic surgery and general anesthesia on postoperative cognitive dysfunction : a phase III double blind, randomized clinical trial
(2016) [Journal article]Postoperative cognitive dysfunction (POCD) is a multifactorial adverse event most frequently in elderly patients. This study evaluated the effect of dexamethasone on POCD incidence after noncardiac and nonneurologic surgery. ... -
Enzyme replacement therapy with pabinafusp alfa for neuronopathic mucopolysaccharidosis II : an integrated analysis of preclinical and clinical data
(2021) [Journal article]Enzyme replacement therapy (ERT) improves somatic manifestations in mucopolysaccharidoses (MPS). However, because intravenously administered enzymes cannot cross the blood–brain barrier (BBB), ERT is ineffective against ... -
Funcionamento cognitivo no transtorno bipolar
(2018) [Thesis]Historicamente, o transtorno bipolar (TB) tem sido tipificado por seus sintomas de humor. No entanto, estudos recentes têm demonstrado que a disfunção cognitiva no TB é prevalente, persistente e heterogênea. Devido ao seu ... -
Functional cognitive disorder presents high frequency and distinct clinical profile in patients with low education
(2022) [Journal article]Introduction: Functional Cognitive Disorder (FCD) is a non-degenerative, common cause of memory complaint in patients with high educational levels. FCD has been insufficiently described in individuals with low education. ... -
Iduronate-2-sulfatase fused with anti-hTfR antibody, pabinafusp alfa, for MPS-II : a phase 2 trial in Brazil
(2021) [Journal article]In Hunter syndrome (mucopolysaccharidosis II [MPS-II]),systemic accumulation of glycosaminoglycans (GAGs) dueto a deficiency of iduronate-2-sulfatase (IDS), caused by mu-tations in theIDSgene, leads to multiple somatic ...
