Browsing by Author "Scholl, Juliete Nathali"
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Avaliação do papel desempenhado por vesículas extracelulares derivadas de glioblastoma na modulação do sistema imune e na progressão tumoral
Scholl, Juliete Nathali (2019) [Dissertation]O glioblastoma (GBM) é o mais maligno e com a menor taxa de sobrevida dos tumores gliais. O tecido tumoral é composto por muitas células neoplásicas em proliferação, fibroblastos e células do sistema imune. A proliferação ... -
Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients
Pietrobon, Anna Julia; Andrejew, Roberta; Custódio, Ricardo Wesley Alberca; Oliveira, Luana de Mendonça; Scholl, Juliete Nathali; Teixeira, Franciane Mouradian Emidio; Brito, Cyro Alves de; Glaser, Talita; Kazmierski, Julia; Goffinet, Christine; Turdo, Anna Claudia; Yendo, Tatiana; Aoki, Valéria; Figueiró, Fabrício; Battastini, Ana Maria Oliveira; Ulrich, Henning; Benard, Gill; Duarte, Alberto Jose da Silva; Sato, Maria Notomi (2022) [Journal article]Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we explored the contribution of extracellular nucleotide ... -
Estabilidade e função de vesículas extracelulares derivadas de glioblastoma
Nunes, Vitoria Brum da Silva; Scholl, Juliete Nathali; Fraga, Amanda; Battastini, Ana Maria Oliveira; Figueiró, Fabrício (2018) [Abstract published in event] -
Exploring CD39 and CD73 expression as potential biomarkers in prostate cancer
Gardani, Carla Fernanda Furtado; Pedrazza, Eduardo Luiz; Paz, Victória Santos; Zanirati, Gabriele Goulart; Costa, Jaderson Costa da; Andrejew, Roberta; Ulrich, Henning; Scholl, Juliete Nathali; Figueiró, Fabrício; Rockenbach, Liliana; Morrone, Fernanda Bueno (2023) [Journal article]Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading ... -
Influência de parâmetros metabólicos, purinérgicos e de comunicação intercelular na imunomodulação e progressão dos gliomas de grau II, III e IV
Scholl, Juliete Nathali (2023) [Thesis]O glioma é um tumor altamente agressivo que apresenta um prognóstico desfavorável. Em parte, a alta agressividade desse tumor está ligada ao grande poder infiltrativo e a grande heterogeneidade tumoral, com a presença de ... -
Lymphocytes from B-acute lymphoblastic leukemia patients present diferential regulation of the adenosinergic axis depending on risk stratifcation
Nunes, Vitoria Brum da Silva; Dias, Camila kehl; Scholl, Juliete Nathali; Sant' Ana, Alexia Nedel; Dias, Amanda de Fraga; Farias, Mariela Granero; Alegretti, Ana Paula; Sosnoski, Monalisa; Daudt, Liane Esteves; Michalowski, Mariana Bohns; Battastini, Ana Maria Oliveira; Paz, Alessandra Aparecida; Figueiró, Fabrício (2022) [Journal article]Purpose Although risk-stratifed chemotherapy regimens improve B-cell acute lymphoblastic leukemia (B-ALL) clinical outcome, relapse occurs in a signifcant number of cases. The identifcation of new therapeutic targets as ... -
Nanoformulation shows cytotoxicity against glioblastoma cell lines and antiangiogenic activity in chicken chorioallantoic membrane
Dallemole, Danieli Rosane; Terroso, Thatiana Ferreira; Alves, Aline de Cristo Soares; Scholl, Juliete Nathali; Onzi, Giovana Ravizzoni; Cé, Rodrigo; Paese, Karina; Battastini, Ana Maria Oliveira; Guterres, Silvia Stanisçuaski; Figueiró, Fabrício; Pohlmann, Adriana Raffin (2021) [Journal article]Glioblastoma (GB) is a histological and genetically heterogeneous brain tumor that is highly proliferative and vascularized. The prognosis is poor with currently available treatment. In this study, we evaluated the ... -
Obesity drives adipose-derived stem cells into a senescent and dysfunctional phenotype associated with P38MAPK/NF-KB axis
Grun, Lucas Kich; Maurmann, Rafael Moura; Scholl, Juliete Nathali; Fogaça, M. E.; Schmitz, Carine Raquel Richter; Dias, Camila kehl; Gasparotto, Juciano; Padoin, Alexandre Vontobel; Mottin, Cláudio Corá; Klamt, Fabio; Figueiró, Fabrício; Jones, Marcus Herbert; Chiela, Eduardo Cremonese Filippi; Guma, Fátima Theresinha Costa Rodrigues; Barbé-Tuana, Florencia María (2023) [Journal article]Background: Adipose-derived stem cells (ADSC) are multipotent cells implicated in tissue homeostasis. Obesity represents a chronic inflammatory disease associated with metabolic dysfunction and age-related mechanisms, with ...